The Department of Surgery at the University of Texas Medical School at Houston
Department of Surgery
LBJ

Faculty Biography

Department of Surgery - Trauma


Yanna Cao, M.D.

Assistant Professor - Research
Department of Surgery
Division of Acute Care Surgery
The University of Texas Medical School at Houston
Center for Translational Injury Research

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Education

1983 MD - Shandong Medical University, P.R. China
1988 MSc - Shandong Medical University, P.R. China
1996 MSc - University of Manitoba, Canada

Academic Appointments

1983-1988 Assistant Professor, Department of Microbiology & Immunology, Shandong Medical University, P.R. China

1988-1993 Lecturer, Department of Microbiology & Immunology, Shandong Medical University, P.R. China

1993-1995 Research Assistant, Department of Immunology, University of Manitoba, Canada.

1995-1998 Research Associate, Department of Internal Medicine/Immunology, University of Manitoba, Canada

1998-1999 Technologist, Blood-Borne Pathogens and Hepatitis, Bureau of Microbiology, Federal Laboratories, Health Canada

1999-2001 Senior Research Associate, Department of Surgery, University of Texas Medical Branch, Galveston, TX

2001-2004 Instructor, Department of Surgery, University of Texas Medical Branch, Galveston, TX

2004-2007 Assistant Professor, Department of Surgery, University of Texas Medical Branch, Galveston, TX

2007-present Assistant Professor, Department of Surgery, University of Texas Health Science Center at Houston, Houston, TX

Adjunct Assistant Professor, Department of Surgery, University of Texas Medical Branch, Galveston, TX

HONORS

1991 Provincial Science and Technology Association of Shandong Province, China

1995 Provincial Outstanding Academic Publication Award, Science and Technology Association of Shandong Province, China

1998 Provincial Outstanding Academic Publication Award, Science and Technology Association of Shandong Province, China

PUBLICATIONS

  1. Cao Y, Li H, Ma D, Huang P. The preparation of biotinylated DNA probe for the detection of heat-stable toxin H in enterotoxigenic E. coli. Chin J Anim Poultry Infect Dis 44:45-47, 1989.
  2. Sun W, Zhang L, Cao Y-L, Cao Y. The correlation study of HBV DNA existing in serum and cancer tissue of patients with hepatocellular carcinoma. Chin J Microbiol Immunol - Clin Microbiol 13:28, 1993.
  3. Sun W, Cao Y-L, Zhang L, Song J, Cao Y. The application of digoxigenin labeled HBV DNA probe for detection of HBV DNA in clinical samples from patient with hepatocellular carcinoma. Chin J Epidemiol 14:157-159, 1993.
  4. Wang D, Sun W, Zhang C, Cao Y, Cao YL, Song J, Zhang L. Detection and localization of hepatitis B virus DNA in hepatocellular carcinoma by in situ hybridization using digoxigenin labeled probe. Acta Adac Med Shandong 31:282-286, 1993.
  5. Cao Y, Sun W, Song J, Wang D, Zhang L, Coa YL. The preparation of HBV-DNA probe labeled with digoxigenin. Acta Adac Med Shandong 31:279-282,1993.
  6. Sun W, Zhang L, Cao Y-L, Song J, Cao Y. The relationship research of HBV gene type with the prediction of hepatocarcinoma. Acta Acad Med Shandong 33:1-3, 1995.
  7. Cao Y, Yang M, Luo Z, Mohapatra SS. Vaccination with a multi-epitopic recombinant allergen induces specific immune deviation via T-cell anergy. Immunology 90:46-51, 1997.
  8. Yang M, Cao Y, Mohapatra SS. CD8+ T cells inhibit immunoglobulin E synthesis in low responder SJL/J mice. Immunology 93:230-237, 1998.
  9. Conery AR, Cao Y, Thompson EA, Townsend Jr. CM, Ko TC, and Luo K. Akt physically interacts with Smad3 to regulate the sensitivity to TGFβ-induced apoptosis. Nature Cell Biology 6:366-372, 2004.
  10. Li F*, Cao Y*, Townsend Jr. CM, and Ko TC. TGF-β signaling in colon cancer cells. World Journal of Surgery 29:306-310, 2005 (* both authors contributed equally).
  11. Alliston T Ko TC, Cao Y, Liang Y-Y, Feng X-H, Chang C, and Derynck R. Repression of bone morphogenetic protein and activin-inducible transcription by Evi-1. Journal of Biological Chemistry 280:24227-24237, 2005.
  12. Nruyen KA*, Cao Y*, Chen JR, Townsend Jr. CM, and Ko TC. Dietary fiber enhances a tumor suppressor signalling pathway in the gut. (* both authors contributed equally). Annals of Surgery 243(5):619-627, 2006.
  13. Cao Y, Deng C, Townsend Jr. CM, Ko TC. TGF- inhibits Akt-induced transformation in intestinal epithelial cells. Surgery 140:322-329, 2006.
  14. Cao Y, Chen L, Zhang W, Liu Y, Papaconstantinou H T, Bush C R, Townsend Jr. CM, Thompson EA, and Ko TC. Identification of apoptotic genes mediating transforming growth factor-beta/Smad3-induced cell death in intestinal epithelial cells using genomic approach. Am J of Physiol Gastrointest Liver Physiol 292: G28-38, 2007
  15. Cao Y, Liu X, Zhang W, Deng X, Zhang H, Liu L, Chen L, Thompson EA, Townsend Jr. CM, Ko TC. TGF-β repression of Id2 induces apoptosis in gut epithelial cells. Oncogene 28:1089–10981-10, 2009

RESEARCH SUPPORT

PO1, NIH, DK35608-19 (PI: Townsend, Courtney M) 06/01/05-03/31/10
"Studies in Gastrointestinal Endocrinology", Project 4 (PI: Ko, Tien C) "Interactions of GI Hormones and TGF-β"
Role: Co-Investigator

P50, NIH, GM038529 (PI: Holcomb, John B) 06/01/07-5/31/09
“Pathogenesis of Multiple Organ Failure”, Project 2 (PI: Ko, Tien C) “Molecular Pathogenesis of Gut Injury in Multiple Organ Failure”
Role: Co-Investigator

Contact Information

Yanna Cao
  • Yanna Cao, MD
  • Assistant Professor - Research
    Department of Surgery
    Division of Acute Care Surgery
    The University of Texas Medical School at Houston

  • Department of Surgery
  • 6431 Fannin Street
    MSB 5.003
    Houston, Texas 77030

  • phone: (713) 500-7224
    e-mail: Yanna.Cao@uth.tmc.edu