Faculty Biography

James M. Cross, MD, FACS

Associate Professor of Surgery
Division of Acute Care Surgery
The University of Texas Medical School at Houston

Medical Director, Burn Intensive Care Unit

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Education:

University of Mississippi
University, Mississippi
Bachelor of Arts (B.A.) - Biology
August 1983 - May 1986

University of Tennessee – Memphis
College of Medicine
Memphis, Tennessee
Doctor of Medicine (M.D.)
August 1987 - May 1991

INTERNSHIP:

The University of Texas Medical School at Houston
Houston, Texas
Department of Surgery
July 1991 - June 1992

RESIDENCY:

The University of Texas Medical School at Houston
Houston, Texas
Department of Surgery
July 1992 - June 1993
July 1995 – June 1998

Research Fellow -
July 1993 – June 1995
Chief Resident
July 1997- June 1998

POSTRESIDENCY CLINICAL EXPERIENCE:

Surgical Critical Care Fellow
The University of Texas Medical School at Houston
Department of Surgery
Houston, Texas
July 1998 – June 1999

ACADEMIC APPOINTMENTS:

Assistant Professor of Surgery
The University of Texas Medical School at Houston
Department of Surgery
Houston, Texas
July 1999 – March 2000

Assistant Professor of Surgery
University of Alabama at Birmingham
Department of Surgery
Birmingham, Alabama
April 2000 – September 2007

Associate Professor of Surgery
University of Alabama at Birmingham
Department of Surgery
Birmingham, Alabama
October 2007 – February 2010

Director, UAB Burn Center
Section of Trauma, Burns, and Surgical Critical Care
Department of Surgery
University of Alabama at Birmingham
October 2000 – February 2010

HOSPITAL APPOINTMENTS:

Attending Surgeon
Houston, Texas
July 1998 – March 2000
Staff - Hermann Hospital
Staff - Harris County Hospital District,
Lyndon B. Johnson General Hospital

Attending Surgeon, UAB University Hospital
Birmingham, Alabama
April 2000 – February 2010

Attending Surgeon
Memorial Hermann Hospital
March 2010- Present

CERTIFICATIONS:

American Board of Surgery #55525
July 1, 2019
American Board of Surgery in
Surgical Critical Care #1727
October 22, 1999

TEACHING:

Instructor, UAB School of Medicine
Department of Nutrition and
Department of Medical Physiology

VISITING PROFESSOR:

University of Mississippi
Sally McDonnell Barksdale Honors College
Visiting Alumni Series
September 2004

COMMITTEES:

Local: University of Alabama at Birmingham
Nutrition Committee, 2000 – 2010

Administration & Recruitment Committee of the
General Surgery Residency Program
2003 – 2010

University of Alabama at Birmingham
Pharmacy and Therapeutics Committee
2005 – 2010

University of Alabama at Birmingham
Tissue Committee
2007 -2010

National: Multicenter Trials Group
2001 - present

American Burn Association
Ethical Issues Committee
2004 – 2007

American Burn Association
Education Committee
2005 – 2011

American Burn Association
Organization & Delivery of Burn Care Committee
2009 - 2011

American Society of Parenteral & Enteral Nutrition
Clinical Practice Committee
2007-2008

State of Alabama Department of Public Health
Regional Trauma Advisory Council
2009 - 2010

EDITORIAL SERVICE:

Reviewer - Nutrition in Clinical Practice

Reviewer – The American Journal of Surgery

Reviewer – Shock

Reviewer – Burns

Reviewer—Journal of Parenteral & Enteral Nutrition

COMMUNITY SERVICE:

Advanced Cardiac Life Support - Provider
June 2003 - present

Advanced Trauma Life Support – Provider
American College of Surgeons
1998 – present

Advanced Trauma Life Support - Instructor
American College of Surgeons
1999 - present

Advanced Burn Life Support - Provider
American Burn Association
January 2001 – present

Advanced Burn Life Support – Instructor
American Burn Association
April 2001 – present

HONORS:

2010 1st Place ABA poster presentation competition.
2008 2nd Place Southern Region Burn Conference Best Physician Paper Award
2006 2nd Place Southern Region Burn Conference Scientific Poster Competition
2002 3rd Place Region IV Burn Conference Poster Competition
1994 Young Investigators Award Competition Finalist,
Seventeenth Annual Conference on Shock
1986 Graduated Cum Laude, University of Mississippi
University, Mississippi
1985 Phi Kappa Phi Honor Society, University of Mississippi
University, Mississippi
1983 – 1987 University Honors Program, University of Mississippi
University, Mississippi

MEDICAL LICENSURE:

Alabama State Board of Medical Examiners
March 2000 - present
Texas State Board of Medical Examiners
July 1992 - present

PROFESSIONAL ORGANIZATIONS:

American College of Surgeons - Fellow (FACS)
American Burn Association
North American Burn Society
Eastern Association for the Surgery of Trauma
Society of Critical Care Medicine
American Society for Parenteral and Enteral Nutrition
Medical Association of the State of Alabama
Southeastern Surgical Congress - Fellow
Surgical Infection Society
International Society for Burn Injuries
Phoenix Society for Burn Survivors

PUBLICATIONS:

Published Abstracts:

1. Mercer DW, Cross JM, Barreto JC, Strobel NHP, Russell DH, Miller TA: Cholecystokinin is a potent protective agent against gastric mucosal injury by acidified ethanol. Gastroenterology 1994; 106(4): A137.

2. Barreto JC, Cross JM, Strobel NHP, Smith GS, Miller TA: A fluorescent marker for the investigation of mild gastric damage: implications for the mechanism of mild irritant protection. Gastroenterology 1994; 106(4): A47.

3. Cross JM, Strobel NHP, Barreto JC, Miller TA: The protective effect of a 21-aminosteroid against hemorrhagic shock induced gastric mucosal damage. Shock 1994; 1(Suppl 1): A19.

4. Cross JM, Mercer DW, Gunter JA, Miller TA: L-dopa induced protection against gastric injury: role of dopamine and alpha2-adenoreceptors. Gastroenterology 1995; 108(4): A76.

5. Mercer DW, Cross JM, Klemm K, Cashman M, Smith GS, Miller TA: Cholecystokinin (CCK) induced gastric protection: role of blood flow and somatostatin (SS). Gastroenterology 1995; 108(4): A165.

6. Mercer DW, Smith GS, Cross JM, Myers SI, Miller TA: Cholecystokinin induced protection against gastric injury is a physiologic effect: role of eicosanoid intermediaries. Gastroenterology 1995; 108(4): A1233.

7. Cross JM, Mercer DW, Miller TA: Effects of dopamine and alpha2-adrenoreceptor blockage on L-dopa induced gastroprotection. Gastroenterology 1996; 110(4): A1379.

8. Mercer DW, Cross JM, Smith GS, Lichtenberger L, Miller TA: Do endogenous gut peptides play a role in gastric mucosal defense? Gastroenterology 1996; 110(4): A194.

9. Cross JM, Chang L, Mercer DW: Effect of Cholecystokinin on gastric injury and gastric mucosal blood flow. Gastroenterology 1997; 112: A1436.

10. Melton SM, McGwin G, May AK, Cross JM, Rue LW. Injury-related mortality is associated with pre-hospital and hospital resource availability. American Association for the Surgery of Trauma. October 2000.

11. McGwin G, Cross JM, Rue LW. Long-Term Trends in Burn Mortality According to Age. Journal of Burn Care and Rehabilitation. March/April 2002. Vol. 23(2): 138.

12. Quinney B, McGwin G, Cross JM, Valent F, Taylor MS, Rue, LW. Thermal Burn Fatalities in the Workplace, United States, 1992-1999. Journal of Burn Care and Rehabilitation. March/April 2002. Vol. 23(2): 163.

13. George RL, McGwin G, Metzger MS, Cross JM, Rue LW. The Effect of Age on Mortality Following Thermal Injury is Not Independent. Journal of Burn Care and Rehabilitation. March/April 2003. Vol. 24(2): S47.

14. Winzeler AH, McGwin G, Rue LW, Cross JM. The Impact of Combined Trauma and Burns on Patient Mortality. Journal of Burn Care and Rehabilitation. March/April 2003. Vol. 24(2): S48.

15. George RL, McGwin G, Metzger MS, Schwacha MG, Cross JM, Chaudry IH, Rue LW. The Association between Gender and Mortality among Burn Patients as Modified by Age. Journal of Burn Care and Rehabilitation. March/April 2003. Vol. 24(2): S49.

16. Quinney B, McGwin G, Cross JM, Taylor AJ, Rue LW. Inhalation Injury and Mortality with Respect to Age. Journal of Burn Care and Rehabilitation. March/April 2003. Vol. 24(2): S150.

17. Bamman MM, Ragan RC, and Cross JM. Myostatin expression after resistance exercise in younger and older men and women. FASEB J. 2003. 17(4):A437.

18. Bamman MM, Ragan RC, and Cross JM. Myogenic regulatory factor expression after resistance exercise in younger and older men and women. Med Sci Sports Exerc. 2003. 35(5 Suppl):S110.

19. Wolf E, Edelman LS, Kemalyan A, Donison L, Cross JM, Underwood M, Palmieri TL, Lawless M, Spence RJ, Goodwin CW, Noppenberger D, Voigt DW, Edwards P, Caruso DM, Foster KN, Hildebrand B, Jeng JC, Crean DA, Purdue GF, Hunt JL, Burris A, Warner PM, Hatfield S, Klein RL, Baker R, Cairns BA, Kessler M, Yowler CJ, Tutolo W, Mozingo DW, Perrin K, Benjamin WS, Villareal C, Saffle JR. Effects of Oxandrolone on Length of Hospital Stay in the Severely Burned: A Multi-Center Prospective Randomized Double-Blind Trial. Journal of Burn Care and Rehabilitation. March/April 2004. Vol. 25(2): S59.

20. Harkins CL, McGwin G, Cross JM, Rue LW. Adrenal Insufficiency in Burn Patients. Journal of Burn Care and Rehabilitation. March/April 2004. Vol. 25(2): S140.

21. Schwacha MG, Cross JM, McGwin G, Hutchinson CB, Rue LW. The Impact of Opiate Analgesics on the Development of Post-Burn Infectious Complications. Journal of Surgical Infections. Spring 2004. Vol. 5(1): 97.

22. McGwin G, George RL, Cross JM, Rue LW. Improving the Ability to Predict Mortality Among Burn Patients. The Journal of Trauma: Injury, Infection, and Critical Care. 2004; Vol. 57(2): 447.

23. Finan KR, Cross JM, McGwin G, Rue LW, Refined Predictors of Burn Mortality in Elderly. Supplement to Journal of Burn Care & Rehabilitation, April 2005. Vol. 26(2): S77.

24. Kim JS, Cross JM, Bamman MM. Age differences in IGF-1 system responses to resistance loading in human skeletal muscle. Med Sci Sports Exerc. 2005.

25. Kosek DJ, Kim JS, Petrella JK, Cross JM, and Bamman MM. Acute changes in mechanogrowth factor and insulin-like growth factor l are related to long-term myofiber hypertrophy. Med Sci Sports Exerc. 2005.

26. Kim JS, Cross JM, and Bamman MM. Effects of age and gender on resistance training-induced changes in myostatin mRNA expression and cell cycle regulation. FASEB J. 19(4):112.31, 2005.

27. Bamman MM, Kosek DJ, Kim JS, Petrella JK, and Cross JM. Utility of the type 11/1 myofiber size ratio as a phenotypic index of sarcopenia. FASEB J. 19(5):903.13, 2005.

28. Bamman MM, Kim JS, and Cross JM. Impact of resistance loading on myogenic gene expression in young and older men and women. Physiologist. 47(4):343, 2004.

29. Kim JS, Cross JM, and Bamman MM. Impact of resistance loading on myostatin expression and cell cycle regulation in young and older men and women. Physiologist. 47(4):343, 2004.

30. Kosek DJ, Petrella JK, Ragan RC, Kim JS, Cross JM, and Bamman MM. Effects of age and gender on myofiber hypertrophy. Physiologist. 47(4):349, 2004.

31. Kim, RS, Ragan RC, Cross JM, and Bamman MM. Acute myogenic responses to resistance exercise: effects of age and gender. FASEB J. 2004.

32. Bamman M, Ragan RC, and Cross JM. Myostatin expression after resistance exercise in younger and older men and women. FASEB J. 17(4):A437, 2003.

33. Petrella JK, Kosek DJ, Kim JS, Cross JM, and Bamman MM. Satellite Cell Activation in Response to 16 Weeks Resistance Loading in Young and Older Adults: 9:45AM-10:00AM: 617. Med Sci Sports Exerc. 2006, May; 38(5 Suppl):S9.

34. Bamman MM, Ragan RC, and Cross JM. Myogenic regulatory factor expression after resistance exercise in younger and older men and women. Med Sci Sports Exerc. 35(5 Suppl):S110, 2003.

35. Quinney, BE, Kerby, JD, Rue, LW, and Cross, JM. Closure of the Mississippi Firefighters Memorial Burn Center: The Implications for Burn Care in Alabama. Journal of Burn Care & Research 2007, November/December 28(6):S190.

36. Merritt, E., Cross, J.M., Bamman, M.M., Protein Synthesis and Degradation Signaling Responses in Skeletal Muscle Following Burn Injury. Journal of Burn Care and Research 2010, March 31(2):S150.

Published Manuscripts:

1. Mercer DW, Cross JM, Barreto JC, Strobel NHP, Miller TA: Cholecystokinin (CCK) induced protection against gastric mucosal injury by acidified ethanol is negated by type “A” CCK receptor blockade. Owen H. Wagensteen Surgical Forum 1994; 45: 133-134.

2. Mercer DW, Cross JM, Barreto JC, Strobel NHP, Russell DH, Miller TA: Cholecystokinin is a potent protective agent against alcohol induced gastric injury in the rat: role of endogenous prostaglandins. Digestive Diseases and Sciences 1995; 40(3): 651-660.

3. Cross JM, Smith GS, Russell DH, Nguyen PH, Mercer DM, Barreto JC, Miller TA: Protective effect of a 21-aminosteroid against hemorrhage-induced ischemia-reperfusion injury in the rat stomach: role of lipid peroxidation. Shock 1995; 3(5): 385-390.

4. Mercer DW, Cross JM, Smith GS, Miller TA: Gastrin-17 is a potent protective agent against mucosal injury. Owen H. Wagensteen Surgical Forum 1995; 46: 125-127.

5. Smith GS, Mercer DW, Cross JM, Barreto JC, Miller TA: Gastric injury induced by ethanol and ischemia-reperfusion in the rat: differing roles of lipid peroxidation and oxygen radicals. Digestive Diseases and Sciences 1996; 41(6): 1157-1164.

6. Cross JM, Mercer DW, Gunter JA, Miller TA: Sensory neuron ablation negates bombesin but not L-dopa induced gastroprotection. Owen H. Wagensteen Surgical Forum 1996; 47: 166-168.

7. Mercer DW, Klemm K, Cross JM, Smith GS, Cashman M, Miller TA: Cholecystokinin-induced protection against gastric injury is independent of endogenous somatostatin. American Journal of Physiology 1996; 271: G692-G700.

8. Mercer DW, Smith GS, Cross JM, Russell DH, Chang L, Cacioppo J: Effects of lipopolysaccharide on intestinal injury: potential role of nitric oxide and lipid peroxidation. Journal of Surgical Research 1996; 63(1): 185-192.

9. Cross JM, Mercer DW, Gunter JA, Miler TA: Effects of dopamine and alpha2-adrenoreceptor blockade on L-dopa and cholecystokinin-induced gastroprotection. Journal of Gastrointestinal Surgery 1997; 1(3): 257-265.

10. Mercer DW, Cross JM, Smith GS, Miller TA: Protective action of gastrin-17 against alcohol-induced gastric injury in the rat: role in mucosal defense. American Journal of Physiology 1997; 273: G365-G373.

11. Cross JM, Chang L, Mercer DW: Effects of Cholecystokinin on gastric injury and gastric mucosal blood flow. Journal of Gastrointestinal Surgery 1998; 2(2): 198-206.

12. Mercer DW, Cross JM, Chang L, Lichtenberger LM: Bombesin prevents gastric injury in the rat: role of gastrin. Digestive Diseases and Sciences 1998; 43(4): 826-833.

13. Mercer DW, Cross JM, Castaneda AA, Gunter JA: Gastroprotective actions of bombesin, L-dopa, and mild irritants: role of prostaglandins and sensory neurons. Surgery 1998; 124(5): 864-870.

14. Cross JM, Marvin RG: Acute colonic pseudo-obstruction in a patient with a significant closed head injury. The Internet Journal of Emergency & Intensive Care Medicine 2000; 4(1): www.ispub.com/journals/IJEICM/Vol4No1/ogilvie.htm. Published January 1, 2000; Last updated January 1, 2000.

15. May AK, Melton SM, McGwin G, Cross JM, Moser SA, Rue LW. Reduction of vacomycin resistant enterococcal infections by limitation of broad-spectrum cephalosporin use in a trauma and burn ICU. Shock 2000; 14:259-264.

16. Taylor AJ, McGwin G, Cross JM, Smith DR, Birmingham BR, Rue LW. Serious Occupational Burn Injuries Treated at a Regional Burn Center. Journal of Burn Care and Rehabilitation. July/August 2002. Vol. 23(4): 244-248.

17. Quinney B, McGwin G, Cross JM, Valent F, Taylor AJ, Rue LW. Thermal burn fatalities in the workplace, United States, 1992-1999. Journal of Burn Care & Rehabilitation, September/October 2002. Vol. 23(5): 305-310.

18. McGwin G, George RL, Cross JM, Reiff DA, Chaudry, IH, Rue LW. Gender differences in mortality following burn injury. Shock. 2002; 18:311-315.

19. McGwin G, Cross JM, Ford JW, Rue LW. Long Term Trends in Mortality According to Age Among Adult Burn Patients. Journal of Burn Care and Rehabilitation, January/February 2003. Vol. 24(1): 21-25

20. Melton SM, McGwin G, Abernathy JH, MacLennan P, Cross JM, Rue LW. Motor vehicle crash-related mortality is associated with prehospital and hospital-based resource availability. Journal of Trauma: Injury, Infection, and Critical Care. 2003; 54(2):273-279.

21. Watts DD, Fakhry SM for the EAST Multi-Institutional HVI Research Group, Cross JM, Contributor/PI. Incidence of Hollow Viscus Injury in Blunt Trauma: An Analysis from 275, 557 Trauma Admissions from the EAST Multi-Institutional Trial. Journal of Trauma: Injury, Infection, and Critical Care. 2003; 54(2):289-294.

22. Fakhry SM, Watts DD, Luchette FA, for the EAST Multi-Institutional HVI Research Group, Cross JM, Contributor/PI. Current Diagnostic Approaches Lack Sensitivity in the Diagnosis of Perforated Blunt Small Bowel Injury: Analysis from 275,557 Trauma Admissions from the EAST Multi-Institutional HVI Trial. Journal of Trauma: Injury, Infection, and Critical Care. 2003; 54(2):295-306.

23. Melton SM, McGwin G, Cross JM, Davidson J, Waller H, Doss MW, Vickers S, Rue LW. Common Bile Duct Transection in Blunt Abdominal Trauma: Case Report Emphasizing Mechanism of Injury and Therapeutic Management. Journal of Trauma: Injury, Infection, and Critical Care. Journal of Trauma: Injury, Infection, and Critical Care. 2003 Apr; 54(4):781-5.

24. Williams MD, Watts D, Fakhry SM, for the EAST Multi-Institutional HVI Research Group, Cross JM, Contributor/PI. Colon Injury after Blunt Abdominal Trauma: Results of the EAST Multi-institutional Hollow Viscus Injury Study. Journal of Trauma: Injury, Infection, and Critical Care. 2003; 55(5):906-912.

25. Moran SG, Windham ST, Cross JM, Melton SM, Rue LW. Vacuum-assisted complex wound closure with elastic vessel loop augmentation: a novel technique. Journal of Wound Care. 2003 Jun; 12(6): 212-3.

26. Bamman MM, Ragan RC, Kim Jeong-su, Cross JM, Hill VJ, Tuggle SC, Allman RM. Myogenic Protein Expression After Resistance Loading in Younger and Older Men and Women. Journal of Applied Physiology. 2004 Oct; 97(4):1329-37.

27. Melton SM, Kerby JD, McGiffin D, McGwin G, Smith JK, Oser RF, Cross JM, Windham ST, Moran SG, Hsia J, Rue LW. The Evolution of Chest Computed Tomography for the Definitive Diagnosis of Blunt Aortic Injury: A Single-Center Experience. Journal of Trauma: Injury, Infection, and Critical Care. 2004; 56(2):243-250.

28. Kim J, Cross JM, Bamman M. Impact of Resistance Loading on Myostatin Expression and Cell Cycle Regulation in Young and Older Men and Women. American Journal of Physiology: Endocrinology and Metabolism. 2005 Jan; 288(6):E1110-E1119.

29. Hawkins, Ashley, MacLennan, Paul A., McGwin, Gerald Jr., and Cross, JM. The Impact of Combined Trauma and Burns on Patient Mortality, The Journal of Trauma, Injury, Infection and Critical Care, 2005 Feb: 58(2):284-288.

30. George, Richard L., McGwin, Gerald Jr., Schwacha, Martin G., Metzger, Jesse, Cross, JM., Chaudry, Irshad H., and Rue, Loring W. The Association Between Sex and Mortality Among Burn Patients as Modified by Age, The Journal of Burn Care & Rehabilitation. 2005 Sept/Oct: 26(5):416-421.

31. Kim JS, Kosek DJ, Petrella JK, Cross JM, and Bamman MM. Resting and load-induced levels of myogenic gene transcripts differ between older adults with demonstrable sarcopenia and young men and women. J. Appl Physiol. 2005 Dec: 99(6): 2149-2158.

32. Wolf, Steven E., Edelman, Linda S., Kemalyan, Nathan, Donison, Lorraine, Cross, James, Underwood, Marcia, Spence, Robert J., Noppenberger, Dene, Palmieri, Tina L., Greenhalgh, David G., Lawless, Marybeth, Voight, David, Edwards, Paul, Warner, Petra, Kagan, Richard, Hatfield, Susan, Jeng, James, Crean, Daria, Hunt, John, Purdue, Gary, Burris, Agnes, Cairns, Bruce, Kessler, Mary, Klein, Robert L., Baker, Rose, Yowler, Charles, Tutulo, Wendy, Foster, Kevin, Caruso, Daniel, Hildebrand, Brian, Benjamin, Wesley, Villarreal, Cynthia, Sanford, Arthur P., and Saffle, Jeffrey. Effects of Oxandrolone on Outcome Measures in the Severely Burned: A Multicenter Prospective Randomized Double-Blind Trial, Journal of Burn Care and Research. 2006 March/April: 131-139.

33. Reiland, A, Hovater, M, McGwin, G., Rue, LW. and Cross, JM. Epidemiology of Intentional Burns. The Journal of Burn Care & Research. 2006 May/June: 27(3): 276-280.

34. Schwacha, MG., McGwin, G., Hutchinson, CB., Cross, JM., MacLennan, PA., and Rue, LW. The Contribution of Opiate Analgesics to the Development of Infectious Complications in Burn Patients. American Journal of Surgery. 192(2006): 82-86.

35. Kerby, JD., McGwin, G., George, RL., Cross, JM., Chaudry, IH., and Rue, LW. Sex Differences in Mortality After Burn Injury: Results of Analysis of the National Burn Repository of the American Burn Association. Journal of Burn Care and Research. 2006 July/August: 452-456.

36. Spann, MD., McGwin, G., Kerby, JD., George, RL., Dunn, S., Rue, LW., Cross, JM. Characteristics of Burn Patients Injured in Methamphetamine Laboratory Explosions. Journal of Burn Care and Research. 2006 July/August: 496-501.

37. Kosek, DJ., Kim, J, Petrella, JK., Cross, JM., and Bamman, MM. Efficacy of 3 days/wk resistance training on myofiber hypertrophy and myogenic mechanisms in young vs. older adults. J. Appl Physiol April 2006. 101:531-544.

38. Petrella, J. K., Cross, J. M., Kosek, D. J., and Bamman, M.M. Efficacy of myonuclear addition may explain differential myofiber growth among resistance trained young and older men and women. Am J Physiol Endocrinol Metab. Am J. Physiol Endocrinol Metab. November 2006. 291 (5): E937-46.

39. Modjarrad, K., McGwin, G., Cross, JM., and Rue, LW. The descriptive epidemiology of intentional burns in the United States: An analysis of the National Burn Repository. Burns. 2007 33 (7): 828-832.

40. Bamman, M.M., Petrella, J.K., Mayhew, D.L., and Cross, J.M. Cluster Analysis Tests the Importance of Myogenic Gene Expression During Myofiber Hypertrophy in Humans. J. Appl. Physiol. June 2007. 102(6): 2232-2239.

41. Kim, J.S., Petrella, J.K., Cross, J.M., and Bamman, M.M. Load-Mediated Down-regulation of Myostatin mRNA Is Not Sufficient To Promote Myofiber Hypertrophy in Humans: A Cluster Analysis. J. Appl. Physiol. Nov 2007. 103(5):1488-1495.

42. Reiff, D.A., Harkins, C.L., McGwin, G. Jr., Cross, J.M. and Rue, L.W. Risk Factors Associated wth Adrenal Insufficiency in Severely Injured Burn Patients. J. Burn Care Res. November/December 2007. 28(6): 854-858.

43. Kim, J.S., Petrella, J.K., Cross, J.M. and Bamman, M.M. Load-Mediated Downregulation of Myostatin mRNA Is Not Sufficient to Promote Myofiber Hypertrophy in Humans: A Cluster Analysis. J. Appl. Physiol. 2007. 103:1488-1495.

44. McGwin, G.Jr., George, R.L., Cross, J.M. and Rue, L.W. Improving the Ability to Predict Mortality Among Burn Patients. Burns 2008. 34 (3): 320-327.

45. Reiff, D.A., Harkins, C.L., McGwin, G., Cross, J.M. and Rue, L.W.3rd. Risk Factors Associated with Adrenal Insufficiency in Severely Injured Burn Patients. J. Burn Care Res. November/December 2007. 28(6):854-858.

46. Petrella, J.K., Kim, J.S., Mayhew, D.L., Cross, J.M. and Bamman, M.M. Potent Myofiber Hypertrophy During Resistance Training in Humans is Associated with Satellite Cell-Mediated Myonuclear Addition: A Cluster Analysis. J. Appl. Physiol. 2008. 104 (6):736-1742.

47. Griffin, R., Poe, A.M., Cross, J.M., Rue, L.W.3rd, McGwin, G. Jr. The Association Between Blood Alcohol Level and Infectious Complications Among Burn Patients. J. Burn Care Res. May/June 2009. 30(3):395-399.

48. Snyder, C.W., Weinberg, J.A., McGwin, G. Jr, Melton, S.M., George, R.L., Reiff, D.A., Cross, J.M., Hubbard-Brown, J., Rue, L.W. 3rd, Kerby, J.D. The relationship of blood product ratio to mortality: survival benefit or survival bias? J Trauma 2009. 66(2):358-62.

49. Mayhew, D. L., Kim, J., Cross, J.M., Ferrando, A. A., Bamman, M. M., Translational Signaling Responses Preceding Resistance Training-Mediated Myofiber Hypertrophy in Young and Old Humans. J Appl Physiol. 2009 107(5): 1655-1662.

50. Thalacker-Mercer, A.E., Dell’Italia, L.J., Cui, X., Cross, J.M., Bamman, M.M., Differential Genomic responses in old vs. young humans despite similar levels of modest muscle damage after resistance loading. Physiol Genomics 2010 Feb 4; 40(3): 141-149.

Other Professional Communications:
1. Munoz, A.J., Butsch, W.S., Morgan, S.L., Heimburger, D.C., Newton, K., Clark, R. and Cross, J.M. Comment on "Nutritional Gain versus Financial Gain: The Role of Metabolic Carts in the Surgical ICU". Letter to the Editor, J. Trauma. 2007. 62 (6): 1539-40.

Invited Presentations:

1. Role of oxygen derived free radicals in gastric mucosal injury. First Annual University of Texas-Houston Surgical Alumni Association Day, Houston, Texas, June 1994.

2. Gastrin-17 is a potent protective agent against gastric mucosal injury. First Annual University of Texas-Houston Research Day, Houston, Texas, October 1995.

3. Surgical History: The Scottish Influence. University of Texas-Houston Medical School, Department of Surgery Grand Rounds, Houston, Texas, June 1998.

4. ARDS. University of Texas-Houston Medical School, Department of Surgery Grand Rounds, Houston, Texas, May 1999.

5. Geriatric Trauma. Twenty-first Life Flight Symposium, Memorial-Hermann Hospital, Houston, Texas, September 25, 1999.

6. Pancreatic Trauma: Update and Review. Southeast Memorial Hospital Grand Rounds, Houston, Texas, December 15, 1999.

7. Enteral Nutrition in trauma and burn patients. 4th Annual Issues in Trauma Conference, Destin, Florida, November 2000.

8. Surgical Nutrition. UAB OMFS Resident Conference, Birmingham, Alabama, December 2000.

9. Surgical Nutrition. UAB Clinical Nurse Update, Birmingham, Alabama, March 2001.

10. Taking Care of the Burn Patient from Injury to Rehab. Burn Course, Birmingham, Alabama, March 2001.

11. Initial Assessment of the Burn Patient. Trauma Symposium, Huntsville, Alabama, May 2001

12. Structure and Function of the UAB Burn Center and the Indicators for Transfer to a Burn Center. UAB Burn Course, Birmingham, Alabama, August 2001.

13. Management Trends In Acute Respiratory Failure. UAB Surgical Grand Rounds, Birmingham, Alabama, August 2001.

14. Nutritional Support in Burn Care. UAB Advanced Burn Course, Birmingham, Alabama, September 2001.

15. Current Management and Cutting Edge Techniques. UAB Advanced Burn Course, Birmingham, Alabama, September 2001.

16. Ventilator Associated Pneumonia. University of Alabama/DCH Grand Rounds, Tuscaloosa, Alabama, September 2001.

17. Initial Assessment of Burn Patients. Fifth Annual UAB Trauma Symposium, Birmingham, Alabama, November 1, 2001.

18. Moderator. 14th Annual Regional Burn Seminar, Chattanooga, Tennessee, December 2001.

19. Recent Innovations in Burn Care. UAB Plastic Surgery Grand Rounds. Birmingham, Alabama, June 2002.

20. Moderator. 15th Annual Regional Burn Seminar, Louisville, Kentucky, December, 2002

21. Caring for the Severely Burned Patient. UAB Emergency Care Conference. Birmingham, Alabama, March 17, 2003.

22. Recent Advances in Burn Care. UAB Surgical Grand Rounds, August 7, 2003.

23. Moderator. 16th Annual Regional Burn Conference, Orlando, Florida, December 2003.

24. Clinical Use of Spray Fibrin Glue in the Treatment of Burn Patients. Tisseel Fibrin Sealant: A Standard of Care in Aesthetic, Reconstructive and Burn Surgery. US/UK Clinical and Scientific Roundtable, Vienna, Austria, October 20-22, 2004.

25. Moderator. 17th Annual Regional Burn Conference, Birmingham, Alabama, November 2004.

26. The Use of Spray Fibrin Sealant in Surgery. UAB Surgical Grand Rounds. December 9, 2004.

27. Trauma Case Studies, UAB Surgical Grand Rounds, Birmingham, Alabama, April 27, 2006.

28. Methamphetamine Injuries. UAB Surgical Grand Rounds, Birmingham, Alabama,
February 12, 2009.

29. The Impact of Methamphetamine/Substance Abuse in Care of the Burn Patient.
American Burn Association Education Symposium, San Antonio, Texas, March 24,
2009.

Presentations:

1. Cholecystokinin is a potent protective agent against gastric mucosal injury by acidified ethanol. American Gastroenterologic Association, New Orleans, Louisiana, May 1994.

2. The protective effect of a 21-aminosteroid against hemorrhagic shock induced gastric mucosal lesions. Shock Society, Big Sky, Montana, June 1994.

3. Cholecystokinin Octapeptide (CCK-OP) induced protection against gastric injury: role of blood flow. The Society of University Surgeons Thirty Seventh Annual University Surgical Residents’ Conference, Denver, Colorado, February 1995.

4. Cholecystokinin (CCK) induced protection: role of blood flow and somatostatin (SS). American Gastroenterologic Association, San Diego, California, May 1995.

5. Cholecystokinin induced protection against gastric injury is a physiologic effect: role of eicosanoid intermediaries. Society for Surgery of the Alimentary Tract, San Diego, California, May 1995.

6. Do endogenous gut peptides play a role in gastric mucosal defense? The Society of University Surgeons Thirty-Eighth Annual University of Surgical Residents’ Conference, Washington DC, February 1996.

7. Do endogenous gut peptides play a role in gastric mucosal defense? South Texas Chapter of the American College of Surgeons, San Antonio, Texas, March 1996.

8. Effects of dopamine and alpha2-adrenoreceptor blockade of L-dopa induced gastroprotection. Eleventh Annual SSAT/Ross Resident and Fellows Conference, Silverado Country Club, Napa Valley, California, May 1996.

9. Effects of Dopamine and alpha2-adrenoreceptor blockade of L-dopa induced gastroprotection. Society for Surgery of the Alimentary Tract, San Francisco, California, May 1996.

10. Sensory neuron ablation negates bombesin but not L-dopa induced gastroprotection. Surgical Forum of the American College of Surgeons, San Francisco, California, October 1996.

11. Effects of Cholecystokinin on gastric injury and gastric mucosal blood flow. South Texas Chapter of American College of Surgeons, San Antonio, Texas, February 1997.

12. Effect of Cholecystokinin on gastric injury and gastric mucosal blood flow. Society for Surgery of the Alimentary Tract, Washington DC, May 1997.

13. Pancreatitis and Abdominal Compartment Syndrome Complicating Severe Burns with Inhalation Injury. 14th Annual Regional Burn Seminar, Chattanooga, Tennessee, December 2001.

14. UAB Burn Support Group: Supporting the Burn Professional. 15th Annual Regional Burn Seminar, Louisville, Kentucky, December 2002.

15. Racial Differences in Complications of Burn Injuries. 16th Annual Regional Burn Conference, Orlando, Florida, December 2003.

16. The Use of Spray Fibrin Glue in Skin Grafting. 17th Annual Regional Burn Conference, Birmingham, Alabama, November 2004.

17. The Use of Spray Fibrin Glue in the Operative Care of Burn Patients. 19th Annual Southern Regional Burn Conference, Durham, NC, November, 2006.

CLINICAL RESEARCH/GRANTS:

Secured:

1. Protocol #499EO2, A Phase 2 Study of Recombinant Human Thrombin (rh Thrombin) Administered Using a Spray Applicator in Subjects Undergoing Autologous Skin Grafting Following Burn of Traumatic Skin Injury. 7-18-06 – 8-17-07, (5%) $31,999. Zymogenetics, Inc. Cross JM (PI).
2. Maximizing Mechanisms of Muscle Hypertrophy to Combat Sarcopenia in Older Adults. 2RO1 AGO17896-06 (Bamman) 4-1-07 – 3-31-12, (5%), $241,578.
3. Etiology, Timecourse, and Functional Sequelae of Age-Associated Sarcopenia. 1-1-2004 – 9-30-2007, (15%) $160,000. VA Medical Research Service(Bamman).
4. Burn Evaluation and Care for Emergency Responders Course. ADPH C80117314 (Peter Ginter PI) $87,413.

Pending:

Targeted Genomics-Proteomics in Muscle Regeneration Across the Human Age Span. 12-1-07 – 11-30-12, (3%), $250,000. RO1 AR055583 NIH/NIAMS (Bamman).
2. Dose-Response Approach to Exercise-Induced Muscle Glucose Uptake Signaling. 12-1-07 – 11-30-12, (5%) $250,000. RO1 DKO80019 NIH/NIDDK (Petrella).

Location & Contact

6431 Fannin Street
MSB 4.020
Houston, Texas 77030
Tel: 713-500-7200
Fax: 713-500-7213

Contact Information

• James M. Cross, MD, FACS

• Associate Professor of Surgery
  Division of Acute Care Surgery
  The University of Texas Medical School at Houston

• Burn Center Director

• Department of Surgery

• 6431 Fannin Street
  MSB 4.150
  Houston, Texas 77030

• phone: (713) 500-7179
  e-mail: James.M.Cross
  @uth.tmc.edu

Executive Assistant :

Karen Harvey