Faculty Biography
Department of Surgery
Division of Acute Care Surgery
John B. Holcomb, MD, FACS
Director, Center for Translational Injury Research
Professor and Vice Chair of the Department of Surgery
Chief of the Division of Acute Care Surgery
Education
College: Centenary College, Shreveport, LA, B.S. in Biology with Honors, Cum Laude
1977-1981
Medical School: University of Arkansas Medical School, Little Rock, AR, M.D. 1981-1985
US Army active duty service, 1985-2008
Clinical Assignments and Responsibilities
1985-1986
General Surgery Intern, William Beaumont Army Medical Center, El Paso, Texas.
1986-1987
Commander and General Medical Officer, U.S. Army Health Clinic, Sinop, Turkey. Responsibilities included providing care for 600 active duty and dependent personnel while serving as the sole physician stationed on an extinct volcano in northern Turkey.
1987-1991
General Surgery Resident, William Beaumont Army Medical Center, El Paso, Texas. Responsibilities included learning general surgery. Additionally, established an ATLS style-training program for military medics prior to their deployment for Operation Desert Shield/Storm.
1991-1994
Staff General Surgeon, Womack Army Medical Center, Ft Bragg, NC.
Responsibilities included directing the medical, surgical intensive care units through the JAHCO inspection, purchasing the initial laparoscopic equipment at Womack, establishing a busy laparoscopic service, and multiple field deployments with the Joint Special Operations Command.
1994-1997
Surgery Attending, General Surgery Service, William Beaumont Army Medical Center, El Paso, TX. Responsibilities included Chief of Trauma, Assistant Chief General Surgery Service, and Assistant Program Director. Established a productive surgical research program.
1997-1999
Chief, Military Trauma Research Branch, U.S. Army Institute of Surgical Research and Surgical Faculty, Brooke Army Medical Center, Ft. Sam Houston, TX. Responsibilities included directing 4 Ph.D.’s and 10 research technicians, focused on hemorrhage control and optimal resuscitation strategies. Directed the branch research priorities, budget, and coordinated the ongoing and proposed protocols. Established a new hemostasis research program at the ISR, spearheading the development of a 5-year research-funding stream totaling over 5 million dollars. Performed general and trauma call duties, while teaching surgical residents.
1999-July 2001
Surgery Faculty, The Ben Taub General Hospital, and Director of the Joint Trauma Training Center, Houston, TX. Responsible for leading a multidisciplinary team of nurses, internal medicine, critical care, and trauma surgeons, coordinating actions with civilian surgical department and military headquarters, interacting with city, state, and federal politicians. Responsibility was to rotate military forward surgical teams through a civilian trauma center. Managed a budget in excess of $500,000 per year. Initiated a comprehensive research program focused on hemorrhage control, optimal resuscitation, and trauma informatics. Initiated a Trauma Simulation Center, using the human patient mannequin to document improvement in team performance. Devised and implemented a strategy that opened three additional Military/Civilian centers at major trauma centers in the U.S.
Aug 2001-July 2002
Surgical Critical Care Fellow, University of Texas at Houston. Major responsibility was learning surgical critical care concepts and techniques. Additionally conducted research focused on surgical critical care, hemorrhage control, and trauma informatics. Took Trauma-attending night call. Served as Trauma Advisor to USSOCOM.
Aug 2002- Jul 2008
Commander of the United States Army Institute of Surgical Research, Ft Sam Houston, TX, and Trauma Consultant for The Army Surgeon General. Command the DoD’s only Surgical Research Laboratory, consisting of 520 personnel, equally focused on a clinical and research mission. Managed a research and personnel budget of 30 million dollars. Established, focused and directed the Combat Casualty Care Research for the Army. Lead efforts to create a clinically active trauma service and oversaw the combination of the two DoD Level-1 trauma centers. Conceived and led efforts to institute across the DoD the Joint Theater Trauma Registry and a Trauma system. Liaison between the DoD and civilian trauma communities. Clinical duties included providing General Surgery, Trauma, Burn, and Critical Care coverage, teaching residents and medical students at Brooke Army Medical Center, the Army’s only Level 1 Trauma Center.
Sep 2008 – Present
Professor of Surgery, University of Texas Health Science Center at Houston. Assume various research, clinical and teaching roles. Director, Center for Translational Injury Research, a new University-wide center focused on translating preclinical research to the clinic. The goal of the new CeTIR is to change clinical practice with quality data, thus improving outcomes. Head, Division of Acute Care Surgery, a new Division encompassing Trauma, Surgical Critical Care, Emergency General Surgery, and Burns. Assume PI status of the existing P-50 Surgery grant and coordinate resubmission. Assume PI status of the T-32 training grant.
Academic Appointments
Assistant Consulting Professor of Surgery, Duke University Medical Center, Durham, NC, 1991-1994
Assistant Professor of Surgery, Uniformed Services University of the Health Sciences,
Bethesda, MD, 1991 – 2001
Associate Professor of Surgery, Uniformed Services University of the Health Sciences, Bethesda, MD, 2001-present
Assistant Professor of Surgery, Baylor College of Medicine, Houston, TX 1999-2001
Clinical Assistant Professor of Surgery, University of Texas, Houston, 2001-2008.
Clinical Professor of Surgery, University of Texas Health Sciences Center, San Antonio, TX, 2006-2008.
Professor of Surgery, University of Texas Health Sciences Center, Houston, TX, 2008-present
Military Leadership Schools:
Officers Basic Course, July 1982
Officer Advanced Course, July 1998
Past Committee Appointments
Chairman, Critical care Committee, Womack Army Medical Center, Ft Bragg, NC, 1991-1994
Medical Student Coordinator, General Surgery Service, William Beaumont Army Medical Center, El Paso, TX, 1994-1997
Tumor Board Chairman, William Beaumont Army Medical Center, El Paso, TX, 1995-1997
IRB and IACUC member, William Beaumont Army Medical Center, El Paso, TX, 1994-1997
IRB member, Institute of Surgical Research, Ft. Sam Houston, TX, 1997-1999
IRB member, Baylor College of Medicine and Affiliated Hospitals, Houston, TX, 1999-2001
Co-Chair-Trauma, NIH Working Group on Strategies for Trauma Resuscitation Research, 2002-2006
Multi-institutional Trials Committee, American Association for the Surgery of Trauma, 2003-2006
Board of Directors, Trauma Institute of San Antonio, TX (TRISAT), 2003-2007
Novo Nordisk Phase 3 Prospective, Randomized rFVIIa Trauma Trial Steering Committee, 2004-2008
Current Committees
Disaster and Medical Special Operations Committee, Eastern Association for the Surgery of Trauma, 2001-present
Committee for Tactical Combat Casualty Care, 2002-present
BAMC Hospital Executive Council, BAMC, 2002-2008
Military Committee Co-Chair, American Association for the Surgery of Trauma, 2005-present
Program Committee, American Association for the Surgery of Trauma, 2006-present
Scholarship Committee, Eastern Association for the Surgery of Trauma, 2006-present
Multi-Institutional Trials Committee, Western Trauma Association, 2006-present
National Trauma Institute, (NTI), Board of Directors, 2007-present
American College of Surgeons, Committee on Trauma, 2007-present
American College of Surgeons Scholarship Committee, 2007-present
Texas EMS Trauma and Acute Care Foundation, Advisory Committee, 2009-present
Chair, Trauma and Injury Subcommittee, Defense Health Board Committee, 2009-present
Technical Expert Panel, Vanderbilt EPC Systematic Evidence Review on Traumatic Brain Injury and Depression, April 2009
Advisor
Trauma Consultant for the Army Surgeon General, 2002-2008
Military Advisor to the Defense Science Board, 2007-present
Mentored Research Fellows
David Kauvar, 2004-2005
Heather Pidcoke, 2005-2008
Neil McMullin, 2005-2006
Joe Kelly, 2006-2007
Amber Ritenour, 2006-2007
Jason Edens, 2007-2008
Kenneth Jastrow, 2008-2009
Jeremy Ward, 2008-2009
Peter Walker, 2008-2010
Ad Hoc Reviewer
Journal of Trauma: Injury, Infection and Critical care
Journal of Anesthesiology
Critical Care Medicine
Journal of the American Medical Association
Journal of the American College of Surgeons
Blood Coagulation & Fibrinolysis
Annals of Surgery
Vox Sanguinis
Lancet
Editorial Board
Trauma
World Journal of Emergency Surgery
Journal of Trauma: Injury, Infection and Critical Care. Section Editor for Military Trauma
NIH Grant Activity
Consultant: Hess (PI), 1U01HL072359-01, "Reducing mortality from acute hemorrhage in trauma." Clinical Research Center Grant in the National Transfusion Medicine/Hemostasis Clinical Research Network. 30 Sep 2002 - 31 Aug 2007
$1.49 million/5 years
Certifications/Licensure
American Board of Surgery, 14 Dec 92, #337762
American Board of Surgery Recertification, expires 1 July 2013
American Board of Surgery, Surgical Critical Care, 18 Oct 04, #2123, Expires 1 Jul 2015
Arkansas Medical License, 21 May 1985, #C-6838, 30 June 2008 (voluntary inactive status)
Texas Medical License, 1998, # K6604, 28 Feb 2010
Organizations
1985-Present. Member, American Medical Association
1991-Present. Fellow, American College of Surgeons
1990-Present. Fellow, Southwestern Surgical Congress
2000-Present. Member, Eastern Association for the Surgery of Trauma
2000-Present. Member, Association of Military Surgeons of the United States
2000-Present, Member, Special Operations Medical Association
2001-Present. Member, American Association for the Surgery of Trauma
2001-Present Member, Houston Surgical Society
2002-Present. Member, American Burn Association
2003-Present. Member, Society of Critical Care Medicine
2004-Present. Member, Western Trauma Association
2005-Present. Member, Shock Society
2007-Present. Member, American Surgical Association
2008-Present. Member, Defense Health Board
Honors
1980 Analytical Chemist of the Year
1981 President, Alpha Epsilon Delta (Pre-Medical Society)
1982 B.S. in Biology with Honors
2001 Order of Military Medical Merit
2001 “A” Designator in Military Surgery
2004 Honorary Medal for Combat Surgical Care (AAST)
2004 U.S. Army’s Greatest Inventions Program for the Chitosan Hemostatic Dressing
2004 The Fitts Lecture: Current Perspective on Combat Casualty Care
2005 Department of the Army Research and Development Achievement Award for Leadership Excellence
2005 U.S. Army’s Greatest Invention for the Combat Application Tourniquet
2006 Award from the Non-Atomic Military Research and Development (NAMRAD), Principals of the Technical Cooperation Program (TTC) for the Small-Volume Hypertonic Fluid Resuscitation for Hemorrhagic Casualty Care, HUMTP-12
2007 U.S. Army’s Greatest Invention for Damage Control Resuscitation
2008 Service award from the American College of Surgery-Committee on Trauma for outstanding scientific contributions to the surgery of trauma and dedication to the care of wounded warriors.
2008 The United States Special Operations Command Medal,
2008 Lifetime Achievement Award in Trauma Resuscitation Science, American Heart Association
2009 University of Texas Chancellor’s Health Fellow for Trauma and Injury
Security Clearance: Top Secret
Military Awards/Decorations:
1985-2008:Joint Meritorious Unit Award (2ed Award), Army Superior Unit Award, Combat Medical Badge, Bronze Star, Legion of Merit, Defense Meritorious Service Medal, Meritorious Service Medal (3rd oak leaf cluster), Joint Services Commendation Medal, Army Commendation Medal (1st oak leaf cluster), Joint Services Achievement Medal (1st oak leaf cluster), National Defense Service Medal, Army Achievement Medal, Armed Forces Expeditionary Medal, Army Service Ribbon, Overseas Ribbon.
Selected Presentations
Holcomb J, Carey S. Malignant Biliary Papillomatosis. Gary Wratten Surgical Symposium, San Francisco, CA, 1991.
Holcomb J and Remar M. Thoracoscopy: First-Year Experience at an Army Medical Center, Gary Wratten Surgical Symposium, 1993.
Holcomb J. Laparoscopic Hernia Repair. Experience at Womack Army Medical Center, Gary Wratten Surgical Symposium, April, 1994.
Holcomb J. Advanced Technology for Combat Casualty Care. Advanced Technology Applications to Combat Casualty Care, Washington, DC, April, 1995.
Holcomb J. Lessons Re-learned from Somalia. 2nd Annual Army Trauma Meeting, San Antonio, TX, September, 1995.
Holcomb J. Management of Mass Casualties. Emergency Department Grand Rounds, R.E. Thomason Hospital, El Paso, TX, October, 1995.
Quetell G, Holcomb J. Laparoscopic Interval Appendectomy. Southern Medical Meeting, Kansas City, MO, November, 1995.
Craig R, Holcomb J. Laparoscopic Repair of Common Bile Duct Injury Using Fibrin Glue in the Porcine Model. Society of Laparoendoscopic Surgeons, Orlando, FL, 7 December 1995.
Hetz S, Holcomb J. Combined Laparoscopic Exploration and Repair of Inguinal Hernias. Emerging Surgical Technologies, Versailles, France, March, 1996.
Holcomb J. Dry Fibrin Sealant Dressing for Hemorrhage Control after Ballistic Injury. Presented at International Fibrin Sealant Meeting, La, Jolla, CA, April, 1996.
Holcomb J. Lessons Learned from Somalia, 1993. Military Medicine Grand Rounds, Uniformed Services University of the Health Sciences, Bethesda, MD, May, 1996.
Thomas D, Hetz S, Holcomb J. Economic and Safety Considerations of Reusable Non-shielded versus Disposable Safety Shielded Trocars. Presented at the Southern Medical Association, Baltimore, MD, November, 1996.
Casto J, Holcomb J. Stage I and II Breast Cancer: A 5-Year Retrospective Treatment Evaluation at William Beaumont Army Medical Center. Presented at the Southern Medical Association, Baltimore, MD, November, 1996.
Tonkinson B, Holcomb J. Cost Analysis: Laparoscopic Nissen Fundoplication Versus Omeprazole. Presented at the Southern Medical Association, Baltimore, MD, November, 1996.
Nessen S, Holcomb J. Patient Satisfaction after Laparoscopic and Open Nissen Fundoplication. Society of Laparoendoscopic Surgeons, Orlando, FL, December, 1996.
Holcomb J. Overview of Dry Fibrin Sealant Dressings for Hemorrhage Control. Special Operations Medical Association, Fayetteville, NC, December, 1996.
Chorens A, Holcomb J, Hetz S. A Prospective, Randomized Comparison of Inguinal Herniorrhaphy: Laparoscopic Preperitoneal vs Open Tension Free vs Open Traditional. 18th Annual Gary P. Wratten Surgical Symposium, Coronado, CA, 9-11 April, 1997.
Holcomb J. Differences in Civilian and Military Trauma. Shock Society, Rio Rancho, CA, June, 1997.
Holcomb J, Pusateri A. Dry Fibrin Sealant Dressings for Hemorrhage Control. Shock Society, Rio Rancho, CA, June, 1997.
Lein B, Holcomb J, Hetz S. Removal of Unexploded Ordinance: Current Recommendations. 3rd Annual Army Trauma Symposium, San Antonio, TX, 24-26 August 1997.
Nessen S, Holcomb J, Hetz S. Treatment Algorithm for Severe Gastroesophageal Reflux Disease Based on Efficacy and Cost Analysis. Society of Laparoendoscopic Surgeons, Endo Expo ‘97, Orlando, FL, 3-6 December 1997.
Holcomb JB. Combat Surgery in Somalia, 1993. Surgery Grand Rounds, University of Maryland Shock Trauma Center. 17 April 1998.
Holcomb JB. Initial Management of Shock and Hemorrhage Control. Vascular Trauma, Current Concepts, Novel Techniques, and Evolving Technologies, San Antonio, TX, 21 May 1998.
Holcomb J, Pusateri A, Hess J, MacPhee M. Dry Fibrin Sealant Dressings for Hemorrhage Control in Swine with Severe Liver Injuries. Oral presentation at the American Association for the Surgery of Trauma, Baltimore, MD, 26 September 1998.
Holcomb JB. Forward Surgery in the U.S. Military. International Committee of the Red Cross Symposium on Prehospital Care of the War Wounded, Geneva Switzerland, November 1998.
Holcomb J, Pusateri A, Harris R, Reid T, Hess J, MacPhee M. Dry Fibrin Sealant Dressings Reduce Blood Loss, Resuscitation Volume and Improve Survival in Hypothermic Coagulopathic Swine with Grade V Liver Injuries. Oral presentation at the Eastern Association for the Surgery of Trauma, Orlando, FL, 15 January 1999.
Holcomb JB. Lessons Relearned from Somalia, 1993: One surgeon’s perspective. American College of Emergency Physicians, San Antonio, TX, 15 March 1999.
Holcomb JB. Dry Fibrin Sealant Dressings Reduce Blood Loss, Resuscitation Volume and Improve Survival in Hypothermic Coagulopathic Swine with Grade V Liver Injuries. Plasma Products Biotechnology Meeting, 1999, Queensland, Australia, 29 March 1999.
Holcomb JB. Efficacy of Fibrin Foam to Decrease Bleeding from Severe Liver Injuries. Plasma Products Biotechnology Meeting, 1999, Queensland, Australia, 29 March 1999.
Holcomb JB. The Army Medic of the Future. Colonel John R. Sperandio Plans, Operations, Intelligence, Training, and Security Postgraduate Short Course, Dallas, TX, 26 April 1999.
Martin RR, Alvarez J, Holcomb JB. Civilian Urban Trauma Experience Approximates Injuries Seen in War for Abdominal Injuries. Presented at the Gary P Wratten, Tacoma, WA, 7 May 1999.
Ellison RW, Holcomb JB, Pusateri AE, Macaitis JM, Brinkley WW, Baskin TW. Hemodynamic and Metabolic Effects of Resuscitation in an Uncontrolled Hemorrhage Model of Severe Rat Liver Injury. Presented at the Gary P Wratten, Tacoma, WA, 7 May 1999.
Holcomb JB. Managing the Massively Bleeding Patient. VI Regional European Congress of the International Society of Blood Transfusion, Jerusalem, Israel, 11 May 1999.
Holcomb JB. New Techniques for Improved Hemorrhage Control. Surgery Grand Rounds, Baylor College of Medicine, Houston, TX, 4 December 1999.
Holcomb JB. Prehospital Care in the 21st Century. American College of Emergency Physicians, Houston, TX, 18 February 2000.
Holcomb JB. New Techniques for Improved Hemorrhage Control. Surgery Grand Rounds, Ryder Trauma Center, Miami FL, 27 April 2000.
Holcomb JB. New Techniques for Improved Hemorrhage Control. Surgery Grand Rounds,
University of Missouri-Kansas City, Kansas City, Missouri, 6-8 July 2000.
Holcomb JB. U.S. Central Command Central Region Medical Symposium 2000. Military Team Training at Ben Taub General Hospital. Tampa, FL, 9 August 2000.
Stamateris C, Holcomb JB. Nursing Implications of Damage Control Surgery. 5th Annual Army Trauma Conference. San Antonio, TX, 22 August 2000.
Holcomb J. NATO Civil-Military Blood Conference. Surgical training, Blood Use and Hemorrhage control. Washington D.C., 9 November 2000.
Holcomb JB. Management of Penetrating Injuries on the Battlefield. Navy Medicine Trauma Symposium. San Diego, CA, 16 November 2000.
Holcomb JB. Dry Fibrin Sealant Dressings Reduce Blood Loss, Resuscitation Volume and Improve Survival in Hypothermic Coagulopathic Swine with Grade V Liver Injuries. Michael E DeBakey International Surgical Society XIII Congress, Houston, TX, 19-21 November 2000.
Holcomb JB. Intravenous rFVIIa Administered for Hemorrhage Control in Hypothermic Coagulopathic Swine with Grade V Liver Injuries. Michael E DeBakey International Surgical Society XIII Congress, Houston, TX, 19-21 November 2000.
Holcomb JB. New Techniques for Improved Hemorrhage Control. Surgery Grand Rounds, Baltimore Shock Trauma, University of Maryland, Baltimore, Maryland, 21-22 January 2001.
Holcomb JB, Schreiber MA. Experimental Use of NovoSeven®: Experiences from Animal Models. 6th Novo Nordisk Symposium on Treatment of Bleeding and Thrombotic Disorders, Copenhagen, Denmark, 3-4 May 2001.
Holcomb JB. Pre-Hospital Combat Fluid Resuscitation Strategy: One of the Lessons Learned in Mogadishu, Somalia. Combat Fluid Resuscitation 2001. USUHS, Bethesda, MD, 18-20 June 2001.
Holcomb JB, Dumire RD, Crommett JW, Stamateris CE, Fagert MA, Cleveland JA, Dorlac GR, Dorlac WC, Mattox KL. Evaluation of Trauma Team Performance Using an Advanced Human Patient Simulator for Resuscitation Training. Accepted for Oral presentation at the American Association for the Surgery of Trauma, Seattle, WA, 14 September 2001.
Holcomb JB. Combined Techniques for Improved Hemorrhage Control. 7th International Tissue Sealants Conference, New Orleans, LA, 6-7 October 2001.
Dumire RD, Crommett JW, Holcomb JB, Stamateris CE, Fagert MA, Cleveland JA, Dorlac GR, Dorlac WC, Mattox KL. Evaluation of Trauma Team Performance Using an Advanced Human Patient Simulator for Resuscitation Training. Oral presentation at the American College of Surgeons, Surgical Forum, New Orleans, LA, 7-12 October 2001.
Holcomb JB. Trauma Lessons Learned from the Battlefield. Pre-Deployment Lecture to the 274th Forward Surgery Team. Ft. Bragg, NC, 13-14 October 2001.
Holcomb JB. New Approaches for Managing Catastrophic Bleeding in the Emergency Department. American College of Emergency Physicians, Breakfast Symposium, Chicago, IL, 15 Oct 2001.
Holcomb JB. New Techniques for Improved Hemorrhage Control. Surgery Grand Rounds, UT-Houston, TX, 16 October 2001.
Holcomb JB. Trauma Lessons Learned from the Battlefield. Pre-Deployment Lecture to the 86th Combat Support Hospital. Ft. Campbell, KY, 8-9 November 2001.
Holcomb JB. Evaluation of Surgical Training Using Simulation. Medicine, Technology and Human Factors in Trauma Care: A Civilian/Military Perspective. University of Maryland, Baltimore, Maryland, 15-16 November 2001.
Holcomb JB. Non-Invasive Pre-Hospital Data Collection. Medicine, Technology and Human Factors in Trauma Care: A Civilian/Military Perspective. University of Maryland, Baltimore, Maryland, 15-16 November 2001.
Holcomb JB. Damage Control Techniques. Definitive Surgical Trauma Skills. Royal College of Surgeons, London, England, 20-22 November 2001.
Schreiber MA, Holcomb JB, Brundage SI, Macaitis JM, Tweardy DJ, Hedner U, Hoots K. The Effect Of Recombinant Factor VIIa on Coagulopathic Pigs with Grade V Liver Injuries. Oral presentation at Eastern Association for the Surgery of Trauma, Tampa Bay, FL, 15-19 January 2002.
Brundage SI, Schreiber MA, Mastrangelo MA, Holcomb JB, Maciatis JM, Moreno CE, Tweardy DJ. Uncontrolled Hemorrhagic Shock in A Porcine Model Leads to Upregulation of the Proinflammatory Cytokines IL-6 and G-CSF and Hepatic Necrosis. Oral presentation at Eastern Association for the Surgery of Trauma, Tampa Bay, FL, 15-19 January 2002.
Holcomb JB, McMullin NR, Kozar RA, Lygas MH, Wright SL, Wright BK, Domonoske BD, Macaitis JM, Sailors RM, Moore FA. Morbidity from Rib Fractures Increases after Age 45. Oral presentation at the Western Trauma Association, Whistler, Canada, 24 February-1 March 2002.
Holcomb JB, Neville HL, Fischer CF, Hoots K. Use of Recombinant FVIIa for Intraperitoneal Coagulopathic Bleeding in a Septic Patient. Oral Presentation at the 24th Annual Gary P Wratten Surgical Symposium, Washington, D.C., 8-10 April 2002.
Niles SE, Holcomb JB, Miller CC, Hinds D, Aoki N, Salinas J, Flannigan TJ, Macaitis JM, Duke JH, Moore FA. Pre-Hospital Physiologic Data and Life-Saving Interventions in Trauma Patients. Oral Presentation at the 24th Annual Gary P Wratten Surgical Symposium, Washington, D.C., 8-10 April 2002.
Brundage SI, Schreiber MA, Holcomb JB, Mastrangelo MA, Xu XQ, Macaitis J, Tweardy DJ. Amplification of the Pro-Inflammatory Transcription Factor Cascade Increases With Severity Of Uncontrolled Hemorrhage in Swine. Oral presentation at the Association for Academic Surgery, Boston, MA, November, 2002.
Kozar RA, Holcomb JB, Macatis J, DeSoignie R, Moore FA. Superior Mesenteric Artery Occlusion (SMAO) Models Shock-Induced Gut Ischemia/Reperfusion. Oral presentation at the Association for Academic Surgery, Boston, MA, November, 2002.
Holcomb JB. Trauma Symposium in Iraq, May-June 2003.
Holcomb JB, Butler F, Geibner S. Tactical Combat Casualty Care Workshop. Presented at the 4th World Congress on Wilderness Medicine, Whistler British Columbia, Canada, 9-13 August 2003.
Holcomb JB. Operation Iraqi Freedom (OIF) AAR, Oral Presentation at the Advanced Technology Applications for Combat Casualty Care Annual (ATACCC) Conference, St. Petersburg, FL, 16-22 August 2003.
Holcomb JB. Improved Hemorrhage Control on the Battlefield, Oral Presentation at the Institute for Defense and Government Advancement (IDGA), Battlefield Healthcare Conference, Chairman, Arlington, VA, 14-17 September 2003.
Holcomb JB. Advances in Hemostasis and the Military Approach to Injuries and Trauma: The First 24 Hours. Oral Presentations at the 6th Annual Steven R. Hall, Trauma Symposium, Ridgedale, MO, 2-4 October 2003.
Holcomb JB. Trauma Surgery in Military and Urban Arenas of Warfare. Oral Presentation at the 2003 American College of Surgeons 89th Annual Clinical Congress, Chicago, IL, 19-23 October 2003.
Holcomb JB. Improved Hemostasis in Trauma Patients. Trauma Grand Rounds at the Oregon Health & Science University, Portland, OR, 16-17 November 2003.
Holcomb JB. Trauma Symposium in Iraq, Jan, 2004.
Martini WZ, Uscilowicz JM, Pusateri AE, Delgado AV, Holcomb JB. Independent Contributions of Hypothermia and Acidosis to Coagulopathy in Swine. Oral Presentation at the EAST meeting, Amelia Island, FL, Jan, 2004.
Holcomb JB. Management of Massive Disasters. Oral Presentation at the 6th World Congress on Trauma, Shock, Inflammation and Sepsis – Pathophysiology, Immune Consequences and Therapy, Munich, Germany, 2-6 March 2004.
Holcomb JB. Prehospital Endpoints of Resuscitation. Oral Presentation at the 24th International Symposium on Intensive and Emergency Medicine, Brussels, Belgium, 30 March- 2 April 2004.
Holcomb JB. Hemorrhage Control Techniques in Trauma. Oral Presentation at the 24th International Symposium on Intensive and Emergency Medicine, Brussels, Belgium, 30 March-2 April 2004.
Holcomb J. Novel Hemostatic Agents and Surgical Combat Casualty Care. Oral Presentation at the Throckmorton Surgical Society Surgical Symposium on Trauma, Des Moines, IA,
16-17 April 2004.
Holcomb JB. Trauma Symposium in Iraq, May-June, 2004.
Holcomb JB. A U.S. Perspective: Recent Experience in Iraq. Oral Presentation at the Management of Battlefield Tissue Injury, Toronto, Canada, 28-29 June 2004.
Holcomb JB. Prediction for Need of Life Saving Interventions Based on Pre-Hospital Trauma Patient Data: Implications for Combat Casualty Care, Oral Presentation at the Advanced Technology Applications for Combat Casualty Care Annual (ATACCC) Conference, St. Petersburg, FL, 18 August 2004.
Holcomb JB. Trauma Update. Oral Presentation at the 10th Annual Field Medicine Conference “Health Service Support in OIF & OEF: Lessons Learned,” Raleigh, NC, 9 September 2004.
Holcomb JB. Bench to Battlefield: Use of rFVIIa. Oral Presentation at the Department of Surgery Grand Rounds, Madigan Army Medical Center, Tacoma, WA, 22-24 September 2004.
Holcomb JB. An Update on Iraq: Resuscitation and Evacuation. Oral Presentation at the Hutchinson Technology Inc., 2nd Annual Directors’ Forum, Maui, Hawaii, 30 September 2004.
Holcomb JB. Current Perspective on Combat Casualty Care. William T Fitts Lecture at the American Association for the Surgery of Trauma, Maui, Hawaii, 29 September-1 October 2004.
Holcomb JB. U.S. Army in Iraq. Oral Presentation at the American College of Surgeons, 90th Annual Clinical Congress, New Orleans, LA, 10-14 October 2004.
Holcomb JB. Adjuncts to Cessation of Bleeding: Fibrin Sealants and rFVIIa. Oral Presentation at the American College of Surgeons, 90th Annual Clinical Congress, New Orleans, LA, 10-14 October 2004.
Holcomb JB. Co-Moderator in the Thrombovascular Resuscitation Session of the Resuscitation Science Symposium (ReSS), New Orleans, LA, 6 November 2004.
Holcomb JB, Cancelada, DA, Cancio, L, Chavez, T, Eastridge, B, Owsley, J. Army Plenary Session for 2004 Association of Military Surgeons of the United States (AMSUS), Trauma Care on the Battlefield Panel Discussion, Denver, CO, 15 November 2004.
Holcomb JB. Clinical Issues Facing Soldiers at War. Oral Presentation at the Association of Military Surgeons of the United States (AMSUS), Denver, CO, 16 November 2004.
Holcomb JB. Combat Casualty Care in Iraq. Oral Presentation, Grand Rounds, University of Texas Health Science-Houston, Houston, TX, 15 December 2004.
Holcomb JB. Manual Vital Signs Reliably Predict Need for Life Saving Interventions in Trauma Patients. Oral Presentation, Eastern Association for the Surgery of Trauma,
Fort Lauderdale, FL, 12 January 2005.
Holcomb JB. What’s New in Combat Casualty Trauma Care: Lessons Learned and Future Directions. Oral Presentation, Government Services Joint Services Symposium, San Antonio, TX, 4 April 2005.
Holcomb JB. Current Perspective on Combat Casualty Care. Oral Presentation, Grand Rounds, University of Pittsburgh, Pittsburgh, PA, 20 April 2005.
Holcomb JB. Human Effects of Explosions in Iraq. Oral Presentation, National Blast Injury Awareness Conference, Alexandria, VA, 9 May 2005
Holcomb JB. Induced Hypothermia – Is It Cool to Chill?? Oral Presentation, 12th Annual University of Southern California Trauma/Critical Care Symposium, Pasadena, CA, 23 May 2005.
Holcomb JB. The Army Experience in Iraq. Oral Presentation, 12th Annual University of Southern California Trauma/Critical Care Symposium, Pasadena, CA, 23 May 2005.
Holcomb JB. Prehospital Heart Rate Variability and Mortality. Oral Presentation, 28th Annual Conference on Shock, Marco Island, FL, 5 June 2005.
Holcomb JB. Theater Trauma Registry/System to Include Advances in Combat Casualty Care. Oral Presentation, 2005 AUSA Medical Symposium, San Antonio, TX, 28 June 2005.
Holcomb JB. KIA and Dow Rates in Iraq and Afghanistan – How are we Doing?” Oral Presentation, 2005 AUSA Medical Symposium, San Antonio, TX, 28 June 2005.
Holcomb JB. Combat Trauma Management: What are the Applications in the Civilian Populations? Oral Presentation, Health Answers Education, Managing Trauma: Expert Opinions on State of the Art and Potential Future, Atlanta, GA, 22 September 2005.
Holcomb JB. Heart Rate Variability in Trauma Patients. Oral Presentation, Surgical Biology Club III Scientific Meeting, San Francisco, CA, 16 October 2005.
Holcomb JB. Systolic Blood Pressure Analysis and Heart Rate Variability. Oral Presentation, American College of Surgeons (ACS), 91st Annual Clinical Congress, San Francisco, CA, 17 October 2005.
Holcomb JB. Research Issues Related to Combat Casualty Care. Oral Presentation, American Philosophical Society Autumn General Meeting, Philadelphia, PA, 11 November 2005.
Holcomb JB. Human Effects of Explosives. Oral Presentation, Blast Injury Conference, Tampa, FL, 15 December 2005.
Holcomb JB. Heart Rate Variability. Oral Presentation. Grand Rounds, University of Texas – Houston Medical School, Houston, TX, 19 January 2006.
Holcomb JB. Current Combat Casualty Care, Oral Presentation. Grand Rounds, University of Texas-Houston Health Science Center, Houston, TX, 9 February 2006.
Holcomb JB. Combat Casualty Care, Oral Presentation. Visiting Professor, Uniformed Services University of Health Sciences, Bethesda, MD, 23 February 2006.
Holcomb JB. Current Status and Challenges of Combat Pain Management. Oral Presentation. TTCP Combat Main Management: Future Direction and Collaboration, Advanced Technology Applications for Combat Casualty Care (ATACCC), St. Pete Beach, FL, 13 August 2006.
Holcomb JB. Damage Control Resuscitation In Iraq. Oral Presentation. Advanced Technology Applications for Combat Casualty Care (ATACCC), St. Pete Beach, FL, 14 August 2006.
Holcomb JB. Casualty Care: Joint Theater Trauma System (JTTS): OIF Wounding Patterns and Statistics Research. Oral Presentation, 2006 TO&E Medical Leaders Conference, Atlanta, GA, 28 August 2006.
Holcomb JB. Combat Casualty Care: The Deadly Triad of Trauma. Oral Presentation. 2006 TO&E Medical Leaders Conference, Atlanta, GA, 28 August 2006.
Holcomb JB. To Cut or Not to Cut? Severe Leg Trauma. Oral Presentation. American College of Surgeons, 92nd Annual Clinical Congress, Chicago, IL, 9 October 2006.
Holcomb JB. Hemostatic Resuscitation. Oral Presentation, American College of Surgeons, 92nd Annual Clinical Congress, Chicago, IL, 12 October 2006.
Holcomb JB. Damage Control Resuscitation. Oral Presentation, Grand Rounds, University of Tennessee, Chattanooga, TN, 18 October 2006.
Holcomb JB. Complex Pulmonary Injuries. Oral Presentation, Critical Care and Trauma Symposium, Harvard Medical School, Boston, MA, 6 November 2006.
Holcomb JB. The Joint Theater Trauma System, Trauma Surgery Research and their DOTMLGP Implications. Oral Presentation, Officer Professional Development, Command and General Staff College, Fort Leavenworth, KS, 21 November 2006.
Holcomb JB. Application of HemCon in Battlefield Extremity Trauma. Oral Presentation, American Academy of Orthopaedic Surgeons, Extremity War Injuries II: Development of Clinical Treatment Principles, Washington, D.C., 24 January 2007.
Holcomb JB. Conducting Research in the Iraq Theater of Operation: Challenges and Possibilities. Oral Presentation, State of the MHS – 2007 Annual Conference, Washington, D.C., 29 January 2007.
Holcomb JB. Hemostatic Resuscitation: Military Experience. Oral Presentation, Trauma, Shock, Inflammation and Sepsis (TSIS) 2007, Munich, Germany, 16 March 2007.
Holcomb JB. Trauma-Trials in the Battlefield. Oral Presentation, Trauma, Shock, Inflammation and Sepsis (TSIS) 2007, Munich, Germany, 17 March 2007.
Holcomb JB. Damage Control – Clinical Outcomes and Research Directions. Oral Presentation, American Association for the Surgery of Trauma – Military Collaboration, Uniformed Services University of the Health Sciences (USUHS), Bethesda, MD, 20 March 2007.
Holcomb JB. When and How to use Damage Control Resuscitation. Oral Presentation, Grand Rounds, University of Wake Forest, Winston-Salem, NC, 11 April 2007.
Holcomb JB. Damage Control Resuscitation: Directly Addressing the Early Coagulopathy of Trauma. Oral Presentation, 2007 Ohio Chapter Annual Meeting, American College of Surgeons, Columbus, Ohio, 12 May 2007.
Holcomb JB. Damage Control Resuscitation. Oral Presentation, Atlanta Surgical Association, Atlanta, GA, 17 May 2007.
Holcomb JB. A National Trauma Institute (NTI). Oral Presentation, National Injury and Shock Institute, Shock Conference, Baltimore, MD, 9 June 2007.
Holcomb JB. Hemostasis, Plenary Session. Oral Presentation, Blast Injury Expert Symposium, London, UK, 12 June 2007.
Holcomb JB. Damage Control From a Resuscitation Point of View. Oral Presentation, Grand Rounds, University of Arkansas Medical School, Little Rock, AR, 10 July 2007.
Holcomb JB. The Need for New Monitors. Oral Presentation, Vital Sign Monitoring for ERCS Symposium, St. Pete Beach, FL, 12 August 2007.
Holcomb JB. Results of Clinical Trials From the War in Iraq and Afghanistan. Oral Presentation. Advanced Technology Application for Combat Casualty Care (ATACCC) Conference, St. Pete Beach, FL, 13 August 2007.
Holcomb JB. Selective Non-Operative Management of Penetrating Abdominal Injury from Combat Fragmentation Wounds. Oral Presentation, Advanced Technology Application for Combat Casualty Care (ATACCC) Conference, St. Pete Beach, FL, 13 August 2007.
Holcomb JB. Massive Blood Transfusion. Oral Presentation, NCABB 35th Annual Meeting, Durham, NC, 10 September 2007.
Holcomb JB. Moderator for Military Session/Trauma Management. American Association for the Surgery of Trauma (AAST) Annual Meeting, Las Vegas, NV, 28 September 2007.
Holcomb JB. What’s New – Military Session. Oral Presentation, American Association for the Surgery of Trauma (AAST) Annual Meeting, Las Vegas, NV, 28 September 2007.
Holcomb JB. Causalities of War. Oral Presentation, The New Yorker Festival, New York City, NY, 6 October 2007.
Holcomb JB. Back to the Future: Whole Blood. Oral Presentation, AABB Annual Meeting & TSPO 2007, Anaheim, CA, 23 October 2007.
Holcomb JB. Novel Approaches to Field Resuscitation of Trauma Session: Trauma Lessons from Iraq. Oral Presentation, American Heart Association Committee for the Resuscitation Science Symposium (ReSS), Orlando, FL, 3 November 2007.
Holcomb JB. Damage Control Resuscitation. Oral Presentation, Kentucky Statewide Trauma Symposium, Louisville, KY, 30 November 2007.
Holcomb JB. Traumatic Injury: Implications and Therapy for Hemostasis. Oral Presentation, Bleeding and Therapeutic Approaches in 2008, New Therapies and New Paradigms Meeting, Atlanta, GA, 6 December 2007.
Holcomb JB. Soldier Medicine. Oral Presentation, Grand Rounds. Beth Israel Deaconess Medical Center, Department of General Surgery, Boston, MA, 19 December 2007.
Holcomb JB. Seminar on Soldier Medicine. Oral Presentation, Institute for Soldier Nanotechnologies, Massachusetts Institute of Technology, Cambridge, MA, 19 December 2007.
Holcomb JB. Orthopedic War Injuries: Lessons for the Trauma Surgeon. Moderator, Military Session, 2008 Eastern Association for the Surgery of Trauma, Jacksonville, FL, 16 January 2008.
Holcomb JB. Department of Defense Heathcare Funding: Priorities & Criteria. Panelist, ABA National Leadership Conference, Washington, D.C., 29 January 2008.
Holcomb JB. Overview of Explosion Physics. Oral Presentation, TBI and PH Plenary Session, 2008 Medical Health System Conference, Washington, D.C., 30 January 2008.
Holcomb JB. Surgical Innovations – Saving Lives in OEF/IEF. Oral Presentation, 2008 Medical Health System Conference, Washington, D.C., 30 January 2008.
Holcomb JB. End Point Initiative Meeting. Meeting Chair, National Trauma Institute, Dallas, TX, 19 February 2008.
Gonzalez EA, Jastrow K, Holcomb JB, Kao LS, Moore FA, Kozar RA. Early Achievement of a 1:2 Ratio of FFP:PRBC. Oral Presentation, Western Trauma Association, Squaw Valley, CA, 26 February 2008.
Holcomb JB, Jurkovich GJ. Point: Counterpoint I. Oral Presentation, Western Trauma Association, Squaw Valley, CA, 27 February 2008.
Holcomb JB. Update Damage Control Resuscitation. Oral Presentation, Damage Control: Bringing Home the Lessons of War, 2nd Collaborative Meeting of the AAST, Bethesda, MD, 12 March 2008.
Holcomb JB. Update on Interventions for Achieving Operative Hemostasis: A Case-Based Approach. Oral Presentation, Cardiovascular and Metabolic Health Foundation and The Postgraduate Institute for Medicine Symposium, Las Vegas, NV, 25 March 2008.
Holcomb JB. Increased Plasma and Platelet to RBC Ratios Improves Outcome in 466 Massively Transfused Civilian Trauma Patients. Oral Presentation, American Surgical Association 128th Annual Meeting, New York City, NY, 25 April 2008.
Holcomb JB. The Wounded Soldier: Advances In Injury Care; Translating the Military Medical Experience to the Civilian Sector. Oral Presentation, Center of Disease Control (CDC), Atlanta, GA, 29 May 2008.
Holcomb JB. Trauma Advances in the Long War. Oral Presentation, AUSA Medical Symposium, Henry B Gonzalez Convention Center, San Antonio, TX, 10 June 2008.
Holcomb JB. Trauma Registries and Outcome, the Trauma Registry from Iraq: Use and Early Results. Oral Presentation, International Shock Congress, Cologne, Germany, 2 July 2008.
Holcomb JB. New Directions in the Management of Trauma Induced Coagulopathy, Looking to the Future of Resuscitation. Oral Presentation, International Shock Congress, Cologne, Germany, 2 July 2008.
Holcomb JB. Lessons from Five Years of War, Taking it to the Front Lines: Damage Control at War, War Surgeon: The Steep Learning Curves. Oral Presentation, San Diego Day of Trauma, November, 2008.
Holcomb JB. Lessons Learned from Iraq Conflict, New Concepts in Transfusion Therapy in the Critically Injured Patient. Oral Presentation, Detroit Trauma Symposium, November, 2008.
Holcomb JB. Oral Presentation, Grand Rounds, Seattle Washington, November, 2008.
Holcomb JB. Minimizing Iatrogenic Resuscitation injury. Grand Rounds, University of Texas. November, 2008.
Holcomb JB. Improving Extremity Hemorrhage Control: Civilian Applications of Combat Products. Katy Emergency Medical Services, December, 2009.
Holcomb JB. Increased Platelet:RBC Ratios are Associated with Improved Survival after Massive Transfusions. Western Trauma Association, February, 2009.
Holcomb JB. Mitigating Iatrogenic Resuscitation Injury. Grand Rounds, Oregon Health and Science University, March, 2009.
Holcomb JB. Adding Plasma to Red Cells. Portland Oregon Surgical Society, March, 2009.
Holcomb JB. Lessons Learned from the Current Battlefield Minimizing Iatrogenic Resuscitation. Keynote Speaker, Annual Trauma Symposium, South Bend, Indiana, March, 2009.
Holcomb JB. Improving Extremity Hemorrhage Control: Civilian Applications of Combat Products. Brazoria County EMS, March, 2009.
Research Support
Dry Fibrin Sealant Dressing for Hemorrhage Control after a Ballistic Injury 1995-96
Principle Investigator $5,000
Special forces Operational Detachment - Delta
Laparoscopic Hernia Repair with Atrium Mesh 1995-96
Principle Investigator $5,000
Atrium Medical
Development and Testing of the Dry Fibrin Sealant Dressing 1996-97
Principle Investigator $25,000 Joint Special Operations Command
Development and Testing of the Dry Fibrin Sealant Dressing 1996-97
Principle Investigator $50,000
USA Medical Research and Material Command
Development and Testing of the Dry Fibrin Sealant Dressing 1996-97
Principle Investigator $94,000
USA Medical Research and Material Command
Development and Testing of the Dry Fibrin Sealant Dressing 1996-97
Principle Investigator $100,000
USA Medical Research and Material Command
Development and Testing of the Dry Fibrin Sealant Dressing 1996-97
Principle Investigator $50,000
American Red Cross
Development and Testing of the Dry Fibrin Sealant Dressing 1997-98
Principle Investigator $182,000
USA Special Operations Command
Optimal Device for Treating Tension Pneumothorax by Combat Medics 1997-98
Principle Investigator $75,000
Marine Corps Combat Development Command
Development and Testing of a Hemostatic Foam for Hemorrhage 1997-99
Control from Non-compressible Hemorrhage $186,000
Principle Investigator
USA Special Operations Command
Evaluation of Fibrin Dressings for Hemorrhage Control in a Simulated 1999-00
Land Mine Injury $100,000 Co- Principle Investigator
American Red Cross
Continuous Physiologic Data Acquisition and Analysis across 2000-01
the Trauma Spectrum $50,000
Principle Investigator
US Army MRMC
Continuous Physiologic Data Analysis after Trauma 2001-02
Principle Investigator $200,000
DARPA
Continuous Physiologic Data Analysis after Trauma 2001-02
Principal Investigator $140,000
US Army MRMC
Prospective Multicenter Transfusion Study in Trauma Patients 2008-10
Co-Investigator $9,200,000
US Army MRMC
Role of the Gut in Post-Injury Multiple Organ Failure 2007-09
Principal Investigator $540,000
National Institutes of Health
Pathogenesis of Multiple Organ Failure 2004-09
Principle Investigator $1,500,000
National Institutes of Health
Publications
1. Mann, EA, Pidcoke HF, Salinas J, Wolf SE, Wade CE, Holcomb JB. Hematocrit causes the most significant error in point of care glucometers. Crit Care Med. 2009 Apr;37(4):1530.
2. Maani CV, Desocio PA, Holcomb JB. Coagulopathy in trauma patients: what are the main influence factors? Curr Opin Anaesthesiol. 2009 Apr;22(2):255-260.
3. Gomez R, Murray CK, Hospenthal DR, Cancio LC, Renz EM, Holcomb JB, Wade CE, Wolf SE. Causes of mortality by autopsy findings of combat casualties and civilian patients admitted to a burn unit. J Am Coll Surg. 2009 Mar;208(3):348-354.
4. Nylund CM, Borgman MA, Holcomb JB, Jenkins D, Spinella PC. Thromboelastography to direct the administration of recombinant activated factor VII in a child with traumatic injury requiring massive transfusion. Pediatr Crit Care Med. 2009 Mar;10(2):e22-6.
5. Kheirabadi BS, Edens JW, Terrazas IB, Estep JS, Klemcke HG, Dubick MA, Holcomb JB. Comparison of new hemostatic granules/powders with currently deployed hemostatic products in a lethal model of extremity arterial hemorrhage in swine. J Trauma. 2009 Feb;66(2):316-26.
6. Holcomb JB, McManus JG, Kerr ST, Pusateri AE. Needle versus tube thoracostomy in a swine model of traumatic tension hemopneumothorax. Prehosp Emerg Care. 2009 Jan-Mar;13(1):18-27.
7. Dewey WS, Richard RL, Hedman TL, Chapman TT, Quick CD, Renz EM, Blackbourne LH, Wolf SE, Holcomb JB. Opposition splint for partial thumb amputation: a case study measuring disability before and after splint use. J Hand Therapy. 2009 Jan-Mar;22(1):79-86.
8. Kragh JF Jr, Walters TJ, Baer DG, Fox CJ, Wade CE, Salinas J, Holcomb JB. Survival with emergency tourniquet use to stop bleeding in major limb trauma. Ann Surg. 2009 Jan;249(1):1-7.
9. Matos RI, Holcomb JB, Callahan C, Spinella PC. Increased mortality rates of young children with traumatic injuries at a US army combat support hospital in Baghdad, Iraq, 2004. Pediatrics. 2008 Nov;122(5):e959-66.
10. Cancio LC, Batchinsky AI, Salinas J, Kuusela T, Convertino VA, Wade CE, Holcomb JB. Heart-rate complexity for prediction of prehospital lifesaving interventions in trauma patients. J Trauma. 2008 Oct;65(4):813-9.
11. Parr MJ, Bouillon B, Brohi K, Dutton RP, Hauser CJ, Hess JR, Holcomb JB, Kluger Y, Mackway-Jones K, Rizoli SB, Yukioka T, Hoyt DB. Traumatic coagulopathy: where are the good experimental models? J Trauma. 2008 Oct;65(4):766-71.
12. Hoyt DB, Dutton RP, Hauser CJ, Hess JR, Holcomb JB, Kluger Y, Mackway-Jones K, Parr MJ, Rizoli SB, Yukioka T, Bouillon B. Management of coagulopathy in the patients with multiple injuries: results from an international survey of clinical practice. J Trauma. 2008 Oct;65(4):755-64.
13. Hess JR, Brohi K, Dutton RP, Hauser CJ, Holcomb JB, Kluger Y, Mackway-Jones K, Parr MJ, Rizoli SB, Yukioka T, Hoyt DB, Bouillon B. The coagulopathy of trauma: a review of mechanisms. J Trauma. 2008 Oct;65(4):748-54.
14. Eastridge BJ, Blackbourne L, Wade CE, Holcomb JB. Radiologic diagnosis of explosion casualties. Am J of Disaster Med. 2008 Sept-Oct;3(5):301-5.
15. Shuja F, Shults C, Duggan M, Tabarra M, Butt MU, Fischer TH, Schreiber MA, Tieu B, Holcomb JB, Sondeen JL, Demoya M, Velmahos GC, Alam HB. Development and testing of freeze-dried plasma for the treatment of trauma-associated coagulopathy. J Trauma. 2008 Nov; 65(5):975-85.
16. Mann EA, Pidcoke HF, Salinas J, Holcomb JB, Wolf SE, Wade CE. The impact of intensive insulin protocols and restrictive blood transfusion strategies on glucose measurement in American Burn Association (ABA) verified burn centers. J Burn Care Res. 2008 Sep-Oct;29(5):718-23.
17. Holcomb JB, Wade CE, Michalek JE, et al. Increased Plasma and Platelet to Red Blood Cell Ratios Improves Outcome in 466 Massively Transfused Civilian Trauma Patients. Ann Surg. 2008 Sep;248(3):447-458.
18. Martini WZ, Cortez DS, Dubick MA, Park MS, Holcomb JB. Thromboelastography is Better than PT, aPTT, and Activated Clotting Time in Detecting Clinically Relevant Clotting Abnormalities After Hypothermia, Hemorrhagic Shock and Resuscitation in Pigs. J Trauma. 2008 Sep;65(3):535-43.
19. Chapman TT, Richard RL, Hedman TL, Chisholm GB, Quick CD, Baer DG, Dewey WS, Jones JS, Renz EM Barillo DJ, Cancio LC, Chung KK, Holcomb JB, Wolf SE. Military Return to Duty and Civilian Return to Work Factors Following Burns With Focus on the Hand and Literature Review. J Burn Care Res. 2008 Aug;29(5):756-62.
20. Mann E, Pidcoke HF, Salinas J, Holcomb JB, Wolf SE, Wade CE. The Impact of Intensive Insulin Protocols and Restrictive Blood Transfusion Strategies on Glucose Measurement in American Burn Association (ABA) Verified Burn Centers. J Burn Care Res. 2008 Aug;29(5):718-23.
21. Murray CK, Loo FL, Hospenthal DR, Cancio LC, Jones JA, Kim SH, Holcomb JB, Wade CE, Wool SE. Incidence of Systemic Fungal Infection and Related Mortality Following Severe Burns. Burns. 2008;34(8):1108-12.
22. Chung KK, Blackbourne LH, Renz EM, Cancio LC, Wang J, Park MS, Horvath EE, Albrecht MC, White CE, Wanek SM, Barillo DJ, Wolf SE, Holcomb JB. Global Evacuation of Burn Patients Does Not Increase the Incidence of Venous Thromboembolic Complications. J Trauma. 2008 Jul;65(1):19-24.
23. Fox CJ, Gillespie DL, Cox ED, Kragh FJ Jr., Mehta SG, Salinas J, Holcomb JB. Damage Control Resuscitation for Vascular Surgery in a Combat Support Hospital. J Trauma. 2008 Jul;65(1):1-9.
24. Griffith ME, Gonzalez RS, Holcomb JB, Hospenthal DR, Wortmann GW, Murray CK. Factors Associated with Recovery of Acinetobacter Baumannii in A Combat Support Hospital. Infec Control Hosp Edimemiol. 2008 Jul;29(7):664-6.
25. Niles SE, McLaughlin DF, Perkins JG, Wade CE, LI Y, Spinella PC, Holcomb JB. Increased Mortality Associated with the Early Coagulopathy of Trauma in Combat Casualties. J Trauma. 2008 Jun;64(6):1459-63; discussion 1463-5.
26. McMullin NR, Hedner U, Ezban M, Lauritzen B, Prince MD, Holcomb JB, Sondeen JL. Recombinant Factor VIIA Reduces Rebleed Hemorrhage Volume in a Swine Aortotomy Model: A Randomized Double-Blinded Study. Shock. 2008 Jun;29(6):703-708.
27. Chapman TT, Richard RL, Hedman TL, Renz EM, Wolf SE, Holcomb JB. Combat Casualty Hand Burns: Evaluating Impairment and Disability during Recovery. J Hand Ther. 2008. Apr-Jun;21(2):150-9.
28. Cho SD, Holcomb JB, Tieu BH, Englehart MS, Morris MS, Karahan ZA, Underwood SA, Muller PJ, Prince MD, Medina L, Sondeen J, Shults C, Duggan M, Tabbara M, Alam HB, Schreiber MA. Reproducibility of an Animal Model Simulating Complex Combat-Related Injury in a Multiple-Institution Format. Shock. 2009 Jan;31(1):87-96.
29. Hess JR, Dutton RB, Holcomb JB, Scalea TM. Giving Plasma at a 1:1 Ratio with Red Cells in Resuscitation: Who Might Benefit? Transfusion. 2008 Aug;48(8):1763-5.
30. Gerhardt RT, De Lorenzo RA, Oliver J, Holcomb JB, Pfaff JA. Out-of-hospital combat casualty care in the current war in Iraq. Ann Emerg Med. 2009 Feb;53(2):169-74.
31. Kheirabadi BS, Crissey JM, Deguzman R, Perez MR, Cox AB, Dubick MA, Holcomb JB. Effects of Synthetic Versus Natural Colloid Resuscitation on Inducing Dilutional Coagulopathy in Hemorrhage in Rabbits. J Trauma. 2008 May;64(5):1213-28; discussion 1228-9.
32. Convertino VA, Ryan KL, Rickards CA, Salinas J, McManus JG, Cooke WH, Holcomb JB. Physiological and Medical monitoring for En Route Care of Combat Casualties. J Trauma. 2008 Apr;64(4 Suppl):S342-53.
33. Salinas J, Drew G, Gallagher J, Cancio LC, Wolf SE, Wade CE, Holcomb JB, Herndon DN, Kramer GC. Closed-loop and Decision-assist Resuscitation of Burn Patients. J Trauma. 2008 Apr;64(4 Suppl):S321-32.
34. Barillo DJ, Renz E, Broger K, Maok B, Wright G, Holcomb JB. An Emergency Medical Bag Set for Long-range Aeromedical Transportation. Am J Disaster Med. 2008 Mar-Apr;3(2):79-86.
35. Hospenthal DR, Murray CK, Andersen RC, et.al. Guidelines for the Prevention of Infection After Combat-Related Injuries. J Trauma. 2008 Mar;64:S211-S220.
36. Owens BD, Kragh JF Jr, Wenke JC, Macaitis J, Wade CE, Holcomb JB. Combat wounds in operation Iraqi Freedom and operation Enduring Freedom. J Trauma. 2008 Feb;64(2):295-9
37. Holcomb JB. Clinical Outcomes from the War: Introduction. J Trauma. 2008 Feb;64:S1
38. Brosch LR, Holcomb JB, Thompson, JC, Cordts, PR. Establishing a Human Research Protection Program in a Combatant Command. J Trauma. 2008 Feb;64:S9-S13.
39. Cordts PR, Brosch LR, Holcomb JB. Now and Then: Combat Casualty Care Policies for Operation Iraqi Freedom and Operating Enduring Freedom Compared With Those of Vietnam. J Trauma. 2008 Feb;64:S14-20.
40. Kelly JF, Ritenour AE, McLaughlin DF, Bagg KA, Apodaca AN, Mallak CT, Pearse L, Lawnick MM, Champion HR, Wade CE, Holcomb JB. Injury Severity and Cause of Death From Operation Iraqi Freedom and Operation Enduring Freedom: 2003-2204 Versus 2006. J Trauma. 2008 Feb;64:S21-S27.
41. Beekley AC, Sebesta JA, Blackbourne LH, Herbert FS, Kauvar DS, Baer DG, Walters, TJ, Mullenix PS, Holcomb JB. 31st Combat Support Hospital Research Group. Prehospital Tourniquet Use in Operation Iraqi Freedom: Effect on Hemorrhage Control and Outcomes. J Trauma. 2008 Feb;64:S28-37.
42. Kragh JF, Walters TJ, Baer DG, Fox CJ, Wade CE, Salinas J, Holcomb JB. Practical Use of Emergency tourniquets to Stop Bleeding in Major Limb Trauma. J Trauma. 2008 Feb;64:S38-S50.
43. Cancio LC, Wade CE, West SA, Holcomb JB. Prediction of Mortality and of the Need for Massive Transfusion in Casualties Arriving at Combat Support Hospitals In Iraq. J Trauma. 2008 Feb;64:S51-S56.
44. McLaughlin DF, Niles SE, Salinas J, Perkins JG, Cox ED, Wade CE, Holcomb JB. A Predictive model for Massive Transfusion in Combat Casualty Patients. J Trauma. 2008 Feb;64:S57-S63.
45. Plotkin AJ, Wade CE, Jenkins DH, Smith KA, Noe JC, Park MS, Perkins JG, Holcomb JB. A Reduction in Clot Formation Rate and Strength Assessed by Thrombelastography is Indicative of transfusion Requirements in Patients With Penetrating Injuries. J Trauma. 2008 Feb;64:S64-S68.
46. Spinella PC, Perkins JG, Grathwohl KW, Beekley AC, Niles SE, McLaughlin DF, Wade CE, Holcomb JB. Effect of Plasma and Red Blood Cell Transfusions on Survival in Patients With Combat Related Traumatic Injuries. J Trauma. 2008 Feb;64:S69-S78.
47. Stinger HK, spinella PC, Perkins JG, Grathwohl KW, Salina J, Martini WZ, Hess JR, Dubick MA, Simon CD, Beekley AC, Wolf, SE, Wade CE, Holcomb JB. The Ratio of Fibrinogen to Red Cells Transfused Affects Survival in Casualties Receiving Massive Transfusions at an Army Combat Support Hospital. J Trauma. 2008 Feb;64:S79-S85.
48. Fox CJ, Gillespie DL, Cox ED, Mehta SG, Kragh JF, Salinas J, Holcomb JB. The Effectiveness of a Damage Control Resuscitation Strategy for Vascular Injury in a Combat Support Hospital: Results of a Case Control Study. J Trauma. 2008 Feb;64:S99-S107.
49. Beekley AC, Blackbourne LH, Sebesta JA, McMullin N, Mullenix, PS, Holcomb JB, Members of the 31st Combat Support Hospital Research Group. Selective Nonoperative management of Penetrating Torso Injury From Combat Fragmentation Wounds. J Trauma. 2008 Feb;64:S108-S117.
50. Schreiber, MA, Zink K, Underwood S, Sullenberger L, Kelly M, Holcomb JB. A Comparison Between Patients Treated at a Combat Support Hospital in Iraq and a Level I Trauma Center in the United States. J Trauma. 2008 Feb;64:S118-S122.
51. Renz EM, Cancio LC, Barillo DJ, White CE, Albrecht MC, Thompson CK, Ennis JL, Wanek SM, King JA, Chung KK, Wolf SE, Holcomb JB. Long Range Transport of War-Related Burn Casualties. J Trauma. 2008 Feb;64:S136-S145.
52. Ennis JL, Chung KK, Renz EM, Barillo DJ, Albrecht MC, Jones JA, Blackbourne LH, Cancio LC, Eastridge BJ, Flaherty SF, Dorlac WC, Kelleher KS, Wade CE, Wolf SE, Jenkins DH, Holcomb JB. Joint Theater Trauma System Implementation of Burn Resuscitation Guidelines Improves Outcomes in Severely Burned Military Casualties. J Trauma. 2008 Feb;64:S146-S152.
53. Ritenour AE, Dorlac WC, Fang R, Woods T, Jenkins DH, Flaherty SF, Wade CE, Holcomb JB. Complications After Fasciotomy Revision and Delayed Compartment Release in Combat Patients. J Trauma. 2008 Feb;64:S153-162.
54. Hedman TL, Renz EM, Richard RL, Quick CD, Dewey WS, Barillo DJ, Cancio LC, Baer DG, Wolf SE, Holcomb JB. Incidence and Severity of Combat Hand Burns After All Army Activity Message. J Trauma. 2008 Feb;64:S169-173.
55. Ritenour AE, Wickley A, Ritenour JS, Kriete BR, Blackbourne LH, Holcomb JB, Wade CE. Tympanic Membrane Perforation and Hearing Loss From Blast Overpressure in Operation Enduring Freedom and Operation Iraqi Freedom Wounded. J Trauma. 2008 Feb;64:S174-178.
56. Chung KK, Juncos LA, Wolf SE, Mann EE, Renz EM, White CE, Barillo DJ, Clark RA, Jones JA, Edgecombe HP, Park MS, Albrecht MC, Cancio LC, Wade CE, Holcomb JB. Continuous Renal Replacement Therapy Improves Survival In Severely Burned Military Casualties With Acute Kidney Injury. J Trauma. 2008 Feb;64:S179-S187.
57. Park MS, Salinas J, Wade CE, Wang J, Martini WZ, Pusateri AE, Merrill GA, Chung KK, Wolf SE, Holcomb JB. Combining Early Coagulation and Inflammatory Status Improves Prediction of Mortality in Burned and Nonburned Trauma Patients. J Trauma. 2008 Feb;64:S188-S194.
58. Gaylord KM, Cooper DB, Mercado JM, Kennedy, JE, Yoder LH, Holcomb JB. Incidence of Posttraumatic Stress Disorder and Mild traumatic Brain Injury in Burned Service Members: Preliminary Report. J Trauma. 2008 Feb;64:S200-S206.
59. Trunkey DD, Johannigman JA, Holcomb JB. Lessons Relearned. Arch Surg. 2008 Feb;143(2):112-4.
60. Batchinsky AI, Wolf SE, Molter N. Kuusela T, Jones JA, Moraru C, Boehme M, Williams K, Bielke P, Wade C, Holcomb JB, Cancio LC. Assessment of Cardiovascular Regulation after Burns by Nonlinear Analysis of the Electrocardiogram. J Burn Care Res. 2008 Jan-Feb;29(1):56-63.
61. Delgado AV, Kheirabadi BS, Fruchterman TM, Scherer M, Cortez D, Wade CE, Dubick MA, Holcomb JB. A Novel Biologic Hemostatic Dressing (fibrin patch) Reduces Blood Loss and Resuscitation Volume and Improves Survival in Hypothermic, Coagulopathic Swine with Grave V Liver Injury. J Trauma. 2008 Jan;64(1):75-80.
62. Mann EA, Salinas J, Pidcoke HF, Wolf SE, Holcomb JB, Wade CE. Error Rates Resulting from Anemia Can Be Corrected in Multiple Commonly Used Point-of-Care Glucometers. J Trauma. 2008 Jan;64(1):15-20; discussion 20-1.
63. Stansbury LG, Lalliss SJ, Branstetter JG, Bagg MR, Holcomb JB. Amputations in U.S. Military Personnel in the Current Conflicts in Afghanistan and Iraq. J Orthop Trauma. 2008 Jan;2291:43-6.
64. Spinella PC, Perkins JG, Grathwohl KW, Repine T, Beekley AC, Sebesta J, Jenkins D, Azarow K, Holcomb JB. Members of the 31st CSH Research Working Group. Fresh Whole Blood Transfusions in Coalition Military, Foreign National, and Enemy Combatant Patients during Operation Iraqi Freedom at a U.S. Combat Support Hospital. World J Surg. 2008 Jan;32(1):2-6.
65. Moore EE, Knudson MM, Schwab CW, Turnkey DD, Johannigman JA, Holcomb JB. Military-Civilian Collaboration in Trauma Care and the Senior Visiting Surgeon Program. N Engl J Med. 2007 Dec 27;357(26):2723-7.
66. Pidcoke HF, Salinas J, Wanek SM, Concannon M, Loo F, Wirfel KL, Holcomb JB, Wolf SE, Wade CE. Patterns of Exogenous Insulin Requirement Reflect Insulin Sensitivity Changes in Trauma. Am J Surg. 2007 Dec;194(6):798-803; discussion 803.
67. Dewey WS, Richard RL, Hedman TL, Chapman TT, Quick DC, Holcomb JB, Wolf SE. A Review of Compression Glove Modifications to Enhance Functional grip: A Case Series. J Burn Care Res. 2007 Nov-Dec;28(6):888-91.
68. Butler FK Jr, Holcomb JB, Giebner SD, McSwain NE, Bagian J. Tactical Combat Casualty Care 2007: Evolving Concepts and Battlefield Experience. Milit Med. 2007 Nov;172(11 Supp):1-19.
69. Stout LR, Jezior JR, Melton LP, Walker JA, Brengman ML, Neumeier ST, Smith RL, Vanfosson CA, Knuth TE, Holcomb JB, Cancio LC. Wartime Burn Care in Iraq: 28th Combat Support Hospital, 2003. Milit Med. 2007 Nov;172(11):1148-53.
70. Kheirabadi Bs, Delgado AV, Dubick MA, Scherer MR, Fedyk CG, Holcomb JB, Pusateri AE. In Vitro Effect of Activated Recombinant Factor VII (rFVIIa) on Coagulation Properties of Human Blood at Hypothermic Temperatures. J Trauma. 2007 Nov;63(5):1079-86.
71. Spinella PC, Perkins JG, Grathwohl KW, Repine T, Beekley AC, Sebesta J, Jenkins D, Azarow K, Holcomb JB; the 31st CSH Research Working Group. Fresh Whole Blood Transfusions in Coalition Military, Foreign National, and Enemy Combatant Patients during Operation Iraqi Freedom at a U.S. Combat Support Hospital. World J Surg. 2008 Jan;32(1):2-6.
72. Martini WZ, Holcomb JB. Acidosis and Coagulopathy: The Differential Effects on Fibrinogen Synthesis and Breakdown in Pigs. Ann Surg. 2007 Nov;246(5):831-5.
73. Mann EA, Pidcoke HF, Salinas J, Wade CE, Holcomb JB, Wolf SE, Lacara T, Domagtoy C, Lickliter D, Quattrocchi K, Snipes L, Kuszai J, Prasnikar M. Accuracy of Gulcometers Should Not Be Assumed. Am J Crit Care. 2007 Nov;16(6):531-2.
74. Spinella PC, Perkins JG, Grathwohl KW, Repine T, Beekley AC, Sebesta J, Jenkins D, Azarow K, Holcomb JB; 31st Combat Support Hospital Research Working Group. Risks Associated with Fresh Whole Blood and Red Blood Cell Transfusions in a Combat Support Hospital. Crit Care Med. 2007 Nov:35(11):2576-81.
75. Borgman MA, Spinella PC, Perkins JG, Grathwohl KW, Repine T, Beekley AC, Sebesta J, Jenkins D, Wade CE, Holcomb JB. The Ratio of Blood Products Transfused Affects Mortality in Patients Receiving Massive Transfusions at a Combat Support Hospital. J Trauma. 2007 Oct;63(4):305-13.
76. Richard R, Hedman TL, Quick CD, Renz EM, Cancio LC, Chung KK, Dewey WS, Barillo DJ, Holcomb JB. Burns. Burns. 2008;34(2):295-6.
77. Schreiber MA, Perkins J, Kiraly L, Underwood S, Wade C, Holcomb JB. Early Predictors of Massive Transfusion in Combat Casualties. J Am Coll Surg. 2007 Oct;205(4):541-545.
78. Batchinsky AI, Cancio LC, Salinas J, Kuusela T, Cooke WH, Wang JJ, Boehme M, Convertino VA, Holcomb JB. Prehospital Loss of R-to-R Interval Complexity is Associated with Mortality in Trauma Patients. J Trauma. 2007 Sep;63(3):512-8.
79. Eastridge BJ, Salinas J, McManus JG, Blackbourne L, Bugler EM, Cooke WH, Convertino VA, Wade CE, Holcomb JB. Hypotension begins at 110 mm Hg: Redefining “Hypotension” with Data. J Trauma. 2007 Aug:63(2):291-7; discussion 297-9.
80. Chung KK, Grathwohl KW, Poropatich RK, Wolf SE, Holcomb JB. Robotic telepresence: past, present and future. J Cardiothorac Vasc Anesth. 2007 Aug;21(4):593-6.
81. Holcomb JB. Damage Control Resuscitation. J Trauma. 2007 Jun:62(6 Suppl):S36-7.
82. McManus JG, Eastridge BJ, Wade CE, Holcomb JB. Hemorrhage Control Research on Today’s Battlefield: Lessons Applied. J Trauma. 2007 Jun;62(6 Suppl):S14.
83. McManus JG, Eastridge BJ, DeWitte M, Greydanus DJ, Rice J, Holcomb JB. Combat Trauma Training for Current Casualty Care. J Trauma. 2007 Jun;62(6 Suppl):S13.
84. Kheirabadi BS, Crissey JM, Deguzman R, Holcomb JB. In Vivo Bleeding Time and In Vitro Thrombelastography Measurements are Better Indicators of Dilutional Hypothermic Coagulopathy Than Prothrombin Time. J Trauma. 2007 Jun;62(6)1252-1361.
85. Sondeen JL, Dubick MA, Holcomb JB, Wade CE. Uncontrolled Hemorrhage Differs from Volume or Pressure Matched Controlled Hemorrhage in Swine. Shock. 2007 Oct;28(4):426-33.
86. Holcomb JB, McMullin NR, Pearse L, Caruso J, Wade CE, Oetjen-Gerdes L, Champion HR, Lawnick M, Farr W, Rodriguez S, Butler FK. Causes of Death in U.S. Special Operation Forces in the Global War on Terrorism: 2001-2004. Ann Surg. 2007 Jun;245(6):986-991.
87. Horvath EE, Murray CK, Vaughan GM, Chung KK, Hospenthal DR, Wade CE, Holcomb JB, Wolf SE, Mason AD Jr, Cancio LC. Fungal Wound Infection (Not Colonization) Is Independently Associated with Mortality in Burn Patients. Ann Surg. 2007 Jun:245(6):978-85.
88. Perkins RM, Aboudara MC, Abbott KC, Holcomb JB. Resuscitative hyperkalemia in noncrush trauma: a prospective, observational study. Clin J Am Soc Nephrol. 2007 Mar;2(2):313-9.
89. Perkins JG, Schreiber MA, Wade CE, Holcomb JB. Early Versus Late Recombinant Factor VIIa in Combat Trauma Patients Requiring Massive Transfusion. J Trauma. 2007 May;62(5):1095-101.
90. Eastridge B, Salinas J, Baskin T. McManus J, Wade C, Holcomb JB. Trend in Shock Index after Injury Predicts Complications, Life Saving Interventions, and Mortality. Acad Emerg Med. 2007 May;14(5 Suppl 1):S138.
91. Tieu BH, Holcomb JB, Schreiber MA. Coagulopathy: its Pathophysiology and Treatment in the Injured Patient. World J Surg. 2007 May;31(5):1055-65.
92. Martini WZ, Dubick MA, Wade CE, Holcomb JB. Evaluation of Tris-hydroxymethylaminomethane on Reversing Coagulation Abnormalities caused by Acidosis in Pigs. Crit Care Med. 2007 Apr 20.
93. Convertino, VA, Cooke WH, Holcomb JB. Letters to the Editor. J Trauma. 2007 Apr;62(4):1070.
94. Convertino VA, Ryan KL, Richards CA, Cooke WH, Idris Ah, Metzger A, Holcomb JB, Adams BD, Lurie KG. Inspiratory Resistance Maintains Arterial Pressure during Central Hypovolemia: Implications for Treatment of Patients with Severe Hemorrhage. Crit Care Med. 2007 Apr;35(4):1145-22.
95. Holcomb JB, Jenkins D, Rhee P, Johannigman J, Mahoney P, Mehta S, Cox ED, Gehrke MJ, Beilman GJ, Schreiber M, Flaherty SF, Grathwohl KW, Spinella PC, Perkins JG, Beekley AC, McMullin NR, Par MS, Gonzalez EA, Wade CE, Dubick MA, Schwab CW, Moore FA, Champion HR, Hoyt DB, Hess JR. Damage Control Resuscitation: Directly Addressing the Early Coagulopathy of Trauma. J Trauma. 2007 Feb;62(2):307-10.
96. Perkins RM, Aboudara MC, Abbott KC, Holcomb JB. Resuscitative Hyperkalemia in Noncrush Trauma: A Prospective, Observational Study. Clin J AM Soc Neprhol. 2007 Mar;2(2):313-9.
97. Gonzalez EA, Moore FA, Holcomb JB, Miller CC, Kozar RA, Todd SR, Cocanour CS, Balldin BC, McKinley BA. Fresh Frozen Plasma Should Be Given Earlier to Patients Requiring Massive Transfusion. J Trauma. 2007 Jan;62(1):112-9.
98. Kheirabadi BS, Acheson EM, Deguzman R, Crissey JM, Delgado AV, Estep SJ, Holcomb JB. The Potential Utility of Fibrin Sealant Dressing in Repair of Vascular Injury in Swine. J Trauma. 2007 Jan;62(1):94-103.
99. Dewey WS, Hedman TL, Chapman TT. Wolf SE, Holcomb JB. The Reliability and Concurrent Validity of the Figure-of-Eight Methods of Measuring Hand Edema in Patients with Burns. J Burn Care Res. 2007 Jan-Feb;28(1):157-62.
100. Hedman TL, Chapman TT, Dewey WS, Quick CD, Wolf Se, Holcomb JB. Two simple leg net devices designed to protect lower-extremity skin grafts and donor sites and prevent decubitus ulcer. J Burn Care Res. 2007 Jan-Feb;28(1):115-9.
101. Walters TJ, Holcomb JB, Cancio LC, Beekley AC, Baer DG. Emergency Tourniquets. J Am Coll Surg. 2007 Jan: 204(1):185-6.
102. Todd SR, McNally MM, Holcomb JB, Kozar RA, Kao LS, Gonzalez EA, Cocanour CS, Vercruysse GA, Lygas MH, Brasseaux BK, Moore FA. A multidisciplinary clinical pathway decreases rib fracture-associated infectious morbidity and mortality in high-risk trauma patients. Am J Surg. 2006 Dec;192(6):806-11.
103. Eastridge BJ, Jenkins D, Flaherty S, Schiller H, Holcomb JB. Trauma System Development in a Theater of War: Experiences From Operation Iraqi Freedom and Operation Enduring Freedom. J Trauma. 2006 Dec;61(6):1366-72, discussion 1372-3.
104. Kheirabadi BS, Sieber J, Holcomb JB. Assessment of the thrombogenic effect of fibrin sealant dressing in a vascular surgery model in rabbits. J Invest Surg. 2006 Nov-Dec;19(6):387-96.
105. Cooke WH, Salinas J, McManus JG, Ryan KL, Richards CA, Holcomb JB, Convertino VA. Heart Period Variability in Trauma Patients May Predict Mortality and Allow Remote Triage. Aviat Space Environ Med. 2006 Nov;77(11):1107-12.
106. Kauvar DS, Wolf SE, Wade CE, Cancio LC, Renz EM, Holcomb JB. Burns sustained in Combat Explosions in Operations Iraqi and Enduring Freedom (OIF/OEF Explosions Burns). Burns. 2006 Nov;32(7):853-7.
107. Eastridge BJ, Owsley J, Sebesta J, Beekley A, Wade C, Wildzunas R, Rhee P, Holcomb JB. Admission Physiology Criteria After Injury on the Battlefield Predict Medical Resource Utilization and Patient Mortality. J Trauma. 2006 Oct: 61(4):820-823.
108. Albrecht MA, Griffith ME, Murray CK, Chung KK, Horvath EE, Ward JA, Hospenthal DR, Holcomb JB, Wolf SE. Impact of Acinetobacter Infection on the Mortality of Burn Patients. J Am Coll Surg. 2006 Oct;203(4):546-50.
109. Chung KK, Blackbourne LH, Wolf SE, White CE, Renz EM, Cancio LC, Holcomb JB, Barillo DJ. Evolution of Burn Resuscitation in Operation Iraqi Freedom. J Burn Care Res. 2006 Sep-Oct;27(5)606-11.
110. McManus JG, Convertino VA, Cooke WH, Ludwig DA, Holcomb JB. R-wave Amplitude in Lead II of an Electrocardiograph Correlates with Central Hypovolemia in Human Beings. Acad Emerg Med. 2006 Oct;13(10):103-10.
111. White CE, Schrank AE, Baskin TW, Holcomb JB. Effects of Recombinant Activated Factor VII in Traumatic Nonsurgical Intracranial Hemorrhage. Curr Surg. 2006 Sep-Oct;63(5):310-7.
112. Convertino VA, Cooke WH, Holcomb JB. Arterial Pulse Pressure and its Association with Reduced Stroke Volume during Progressive Central Hypovolemia. J Trauma. 2006 Sep;61(3):629-34.
113. McMullin NR, Kauvar DS, Currier HM, Baskin TW, Pusateri AE, Holcomb JB. The Clinical and Laboratory Response to Recombinant Factor VIIa in Trauma and Surgical Patients with Acquired Coagulopathy. Curr Surg. 2006 Jul-Aug:634:246-51.
114. Holcomb JB, Kheirabadi BS, Wade CE. Letters to the Editor. J Trauma. 2006 Jul:61(1):241.
115. Kauvar DS, Holcomb JB, Norris GC, Hess Jr. Fresh whole blood transfusion: a Controversial military practice. J Trauma. 2006 Jul;61(1):181-4.
116. Martini WZ, Dubick MA, Pusateri AE, Park MS, Ryan KL, Holcomb JB. Does bicarbonate correct coagulation function impaired by acidosis in Swine? J Trauma. 2006 Jul;61(1):99-106.
117. Wolf SE, Kauvar DS, Wade CE, Cancio LC, Renz EP, Horvath EE, White CE, Park MS, Wanek S, Albrecht MA, Blackbourne LH, Barillo DJ, Holcomb JB. Comparison Between Civilian Burns and Combat Burns from Operation Iraqi Freedom and Operation Enduring Freedom. Ann Surg. 2006 Jun;243(6):786-92; discussion 792-5.
118. Ciraulo DL, Barie PS, Briggs SM, Bjerke HS, Born CT, Capella J, Cancio L, Dennis A, Digiacomo JC, Gross RI, Hammond JS, Holcomb JB, Jenkins D, Knuth TE, Letarte PB, Lynn M, O’Neill PA, Salomone JP, Shatz DV. An Update on the Surgeons Scope and Depth of Practice to all Hazards Emergency Response. J Trauma. 2006 Jun;60(6):1267-74.
119. Eastridge BJ, Malone D, Holcomb JB. Early Predictors of Transfusion and Mortality After Injury: A Review of the Data-Based Literature. J Trauma. 2006 Jun;60(6 Suppl):S20-S25.
120. Holcomb JB, Hess JR. Early Massive Trauma Transfusion: State of the Art: Editors’ Introduction. J Trauma. 2006 Jun;60(6Supple):S1-2.
121. Kozar RA, Moore FA, Cothren CC, Moore EE, Sena M., Bulger EM, Miller CC, Eastridge B, Acheson E, Brundage SI, Tataria M, McCarthy M, Holcomb JB. Risk Factors for Hepatic Morbidity Following Nonoperative Management: Multicenter Study. Arch Surg. 2006 May;141(5):451-8; discussion 458-9.
122. Hess JR, Holcomb JB, Hoyt DB. Damage Control Resuscitation: The Need for Specific Blood Products to Treat the Coagulopathy of Trauma. Transfusion. 2006 May:46(5):685-6.
123. Cancio LC, Galvez E Jr, Turner CE, Kypreos NG, Parket A, Holcomb JB. Base Deficit and Alveolar-Arterial Gradient during Resuscitation Contribute Independently but Modestly to the Prediction of Mortality After Burn Injury. J Burn Care Res. 2006 May-Jun;27(3):280-96.
124. Kauvar DS, Cancio LC, Wolf SE, Wade CE, Holcomb JB. Comparison of Combat and Non-combat Burns from Ongoing U.S. Military Operations. J Surg Res. 2006 May 15; 132(2):196-200.
125. Pusateri AE, Holcomb JB, Kheirabadi BS, Alam HB, Wade CE, Ryan KL. Making Sense of the Preclinical Literature on Advanced Hemostatic Products. J Trauma. 2006 Mar;60(3):674-82.
126. Wedmore I, McManus JG, Pusateri AE, Holcomb JB. A Special Report on the Chitosan-Based Hemostatic Dressing: Experience in Current Combat Operations. J Trauma. 2006 Mar;60(2):655-8.
127. Cooke WH, Salinas J, Convertino VA, Ludwig DA, Hinds D, Duke JH, Moore FA, Holcomb JB. Heart rate variability and its association with mortality in prehospital trauma Patients. J Trauma. 2006 Feb:60(2):363-70; discussion 370.
128. Holcomb JB, Stansbury LG, Champion HR, Wade C, Bellamy RF. Understanding Combat Casualty Care Statistics. J Trauma. 2006 Feb;60(2):397-401..
129. Kozar RA, Moore JB, Niles SE, Holcomb JB, Moore EE, Cothren CC, Hartwell E, Moore FA. Complications of Nonoperative Management of High-Grade Blunt Hepatic Injuries. J Trauma. 2005 Nov;59(5):1066-1071.
130. Holcomb JB. The 2004 Fitts Lecture: Current Perspective on Combat Casualty Care. J Trauma. 2005 Nov;59(4):990-1002.
131. Martini WZ, Chinkes DL, Pusateri AE, Holcomb JB, Yu YM, Zhang XJ, Wolfe RR. Acute Changes in Fibrinogen Metabolism and Coagulation after Hemorrhage in Pigs. AM J Physiol Endocrinol Metab. 2005 Nov;289(5):Epub 2005 Jun 14.
132. McManus J, Yershov AL, Ludwig D, Holcomb JB, Salinas J, Dubick MA, Convertino VA, Hinds D, David W, Flanagan T, Duke JH. Radial Pulse Character Relationships to Systolic Blood Pressure and Trauma Outcomes. Prehosp Emerg Care. 2005 Oct-Dec;9(4):423-8.
133. Walters TJ, Wenke JC, Kauvar DS, McManus JG, Holcomb JB, Baer DG. Effectiveness of Self-applied Tourniquets in Human Volunteers. Prehosp Emerg Care. 2005 Oct-Dec;9(4):416-22.
134. Acheson EM, Kheirabadi BS, Deguzman R, Dick EJ Jr, Holcomb JB. Comparison of Hemorrhage Control Agents Applied to Lethal Extremity Arterial Hemorrhages in Swine. J Trauma. 2005 Oct;59(4):865-74; discussion 874-5..
135. Holcomb JB, Salinas J, McManus JM, Miller CC, Cooke WH, Convertino VA. Manual Vital Signs Reliably Predict need for Life-saving Interventions in Trauma Patients. J Trauma. 2005 Oct;59(4):821-9; discussion 828-9.
136. Dorlac WC, DeBakey ME, Holcomb JB, Fagan SP, Kwong Kl, Dorlac GR, Schreiber MA, Persee DE, Moore FA , Mattox K. Mortality from Isolated Civilian Penetrating Extremity injury. J Trauma. 2005 Jul;59(1):217-22.
137. Klemcke HG, Delgado A, Holcomb JB, Ryan KL, Burke A, DeGuzman R, Scherer M, Cortez D, Uscilowicz J, Macaitis JM, Bliss J, Wojtaszczyk J, Christensen S, Currier H, Pusateri AE. Effect of Recombinant FVIIa in Hypothermic, Coagulopathic Pigs with Liver Injuries. J Trauma. 2005 Jul;59(1):155-61; discussion 161.
138. Kheirabadi BS, Acheson EM, DeGuzman R, Sondeen JL, Ryan KL, Delgado A, Dick EJ Jr, Holcomb JB. Hemostatic Efficacy of Two Advanced Dressings in an Aortic Hemorrhage Model In Swine. J Trauma. 2005 Jul;59(1):25-34, discussion 34-5.
139. Wade CE, Holcomb JB. Endpoints in Clinical Trials of Fluid Resuscitation of Patients with Traumatic Injuries. Transfusion. 2005 Jul; 45 Suppl:4S-8S. Review.
140. Holcomb JB. Use of Recombinant Activated Factor VII to Treat the Acquired Coagulopathy of Trauma. J Trauma. 2005 Jun;58(6):1298-303. Review.
141. Holcomb JB, Hoots K, Moore FA. Treatment of an Acquired Coagulopathy with Recombinant Activated Factor VII in a damage-control Patient. Mild Med. 2005 Apr;170(4):287-90.
142. Butler F, Holcomb JB. The Tactical Combat Casualty Care Transition Initiative. Army Medical Department Journal. 2005 Apr.
143. Barillo DJ, Jordan MH, Jocz RJ, Nye D, Cancio LC, Holcomb JB. Tracking the Daily Availability of Burn Beds for National Emergencies. J Burn Care Rehabil. 2005 Mar-Apr; 26(2):174-82.
144. Mozingo DW, Barillo DJ, Holcomb JB. The Pope Air Force Base Aircraft Crash and Burn Disaster. J Burn Care Rehabil. 2005 Mar-Apr;26(2):132-40.
145. Barillo DJ, Cancio LC, Hutton BG, Gueller GE, Holcomb JB. Combat Burn Life Support: A Military Burn Education Program. J Burn Care Rehabil. 2005 Mar-Apr;26(2):162-5.
146. Cancio LC, Horvath EE, Barrillo DJ, Kopchinski BJ, Charter KR, Montalvo AE, Buescher TM, Brengman ML, Brandt MM, Holcomb JB. Burn Support for Operation Iraqi Freedom and Related Operations, 2003 to 2004. J Burn Care Rehabil. 2005 Mar-Apr;26(2):151-61.
147. Martini WZ, Pusateri AE, Usciliowicz JM, Delgado AV, Holcomb JB. Independent Contributions of Hypothermia and Acidosis to Coagulopathy in Swine. J Trauma. 2005 May;58(5):1002-9; discussion 1009-10.
148. Wojcik BF, Stein CR, Devore RB Jr., Hassell LH, Holcomb JB. Status of Trauma Care in U.S. Army Hospitals. Mil Med. 2005 Feb;170(2):141-8.
149. Lurie KG, Idris A, Holcomb JB. Level 1 Cardiac Arrest Centers: Learning from the Trauma Surgeons. Acad Emer Med. 2005 Jan;12(1):79-80.
150. Holcomb JB, Niles SE, Miller CC, Hinds D, Duke JH, Moore FA. Pre-hospital Physiologic Data and Lifesaving Interventions in Trauma Patients. Mil Med. 2005 Jan;170(1):7-13.
151. Dubick MA, Brooks DE, Macaitis JM, Bice TG, Moreau AR, Holcomb JB. Evaluation of Commercially Available Fluid-Warming Devices for Use in Forward Surgical and Combat Areas. Mil Med. 2005 Jan;170(1):76-82.
152. Kirkpatrick AW, Campbell MR, Jones JA, Broderick TJ, Ball CG, McBeth PB, McSwain NE, Hamilton DR, Holcomb JB. Extraterrestrial hemorrhage control: terrestrial developments in technique, technology, and philosophy with applicability to traumatic hemorrhage control in long-duration space flight. J Am Coll Surg. 2005 Jan;200(1):64-76.
153. Mohr Am, Holcomb JB, Dutton RP, Duranteau J. Recombinant Activated Factor VIIa and Hemostatis in Critical Care: a Focus on Trauma. Crit Care. 2005;9 Suppl 5:S37-42.
154. Schreiber MA, Holcomb JB, Rojkjaer R. Preclinical Trauma studies of Recombinant Factor VIIa. Crit Care. 2005;9 Suppl 5:S25-8.
155. Zhang JN, Wood J. Bergeron AL, McBride L, Ball C, Yu Q, Pusateri AE, Holcomb JB, Dong J. Effects of Low Temperature on Shear-induced Platelet Aggregation and Activation. J Trauma. 2004 Aug;57(2):216-23.
156. Pusateri AE, Kheirabadi BS, Delgado AV, Doyle JW, Kanellos J, Uscilowics JM, Martinez RS, Holcomb JB, Modrow HE. Structural Design of the Dry Fibrin Sealant Dressing and Its Impact on the Hemostatic Efficacy of the Product. J Biomed Mater Res. 2004 Jul 15;70B(1):114-21.
157. Brundage SI, Zautke NA, Holcomb JB, Spain DA, Lam JC, Mastrangelo MA, Macaitis JM, Tweardy DJ. Interleukin-6 infusion blunts proinflammatory cytokine production without causing systematic toxicity in a swine model of uncontrolled hemorrhagic shock. J Trauma. 2004 Nov; 57(5)970-7, discussion 977-8.
158. Pusateri AE, Delgado AV, Dick EJ Jr, Martinez RS, Holcomb JB, Ryan KL. Application of a granular mineral-based hemostatic agent (QuikClot) to reduce blood Loss after grade V liver injury in swine. J Trauma. 2004 Sep;57(3):555-62; discussion 562.
159. Sondeen JL, Pusateri AE, Hedner U, Yantis LD, Holcomb JB. Recombinant Factor VIIa Increases the Pressure at which Rebleeding Occurs in Procine Uncontrolled Aortic Hemorrhage Model. Shock. 2004 Aug;22(2):163-8.
160. Kotwal RS, O’Connor KC, Johnson TR, Mosely DS, Meyer DE, Holcomb JB. A Novel Pain Management Strategy for Combat Casualty Care. Ann Emerg Med. 2004 Aug;44(2):121-7.
161. Kozar RA, Holcomb JB, Hassoun HT, Macaitis J, DeSoignie R, Moore FA. Superior Mesenteric Artery Occlusion Models Shock-Induced Gut Ischemia- Reperfusion: Models Of Shock-Induced Gut Ischemia. J Surg Res. 2004 Jan; 116(1):145-50.
162. Holcomb JB. Combat Triage. NATO Emergency War Surgery Handbook. 2004.
163. Holcomb JB. Methods for Improved Hemorrhage Control. Critical Care. 2004;8(Suppl 2):S57-S60.
164. Hoyt DB, Holcomb JB, Abraham E, Atkins J, Sopko G. Working Group on Research Program Summary Report: National Heart Lung Blood Institute NHLBI), National Institute of General Medical Sciences (NIGMS), and National Institute of Neurological Disorders and Stroke (NINDS) of the National Institutes of Health (NIH), and the Department of Defense (DoD). J Trauma. 2004 Aug;57(2):410-15.
165. Pusateri AE, Modrow HE, Harris RA, Holcomb JB, Hess JR, Mosebar RH, Reid TJ, Nelson JH, Goodwin CW, Fitzpatrick GM, McManus AT, Zolock DT, Sondeen JL, Cornum RL, Martinez RS. Advanced Hemostatic Dressing Development Program: Animal Model Selection Criteria and Results of a Study of Nine Hemostatic Dressings in a Model of Severe Large Venous Hemorrhage and Hepatic Injury in Swine. J Trauma. 2003 Sep; 55(3):518-26.
166. Brundage SI, Schreiber MA, Holcomb JB, Zautke N, Mastrangelo MA, Xq X, Macaitis J, Tweardy DJ. Amplification of the Proinflammatory Transcription Factor Cascade Increases With Severity of Uncontrolled Hemorrhage in Swine. J Surg Res. 2003 Jul;113(1):74-80.
167. Holcomb JB, Neville HL, Fischer CF, Hoots K. Use of Recombinant FVIIa for Intraperitoneal Coagulopathic Bleeding in a Septic Patient. Current Surgery. 2003 Jul-Aug;60(4): 423-7.
168. Bruce S, Bridges EJ, Holcomb JB. Preparing to respond: Joint Trauma Training Center and USAF Nursing Warskills Simulation Laboratory. Crit Care Nurs Clin North Am. 2003 Jun;15(2):149-62.
169. Balogh Z, McKinley BA, Holcomb JB, Miller CC, Cocanour CS, Kozar RA,Valdivia A, Ware DN, Moore FA. Both Primary and Secondary Abdominal Compartment Syndrome Can Be Predicted Early and are Harbingers of Multiple Organ Failure. J Trauma. 2003 May;54(5):848-57; discussion 859-61.
170. Sondeen JL, Coppes VG, Holcomb JB. Blood Pressure at which Rebleeding Occurs after Resuscitation in Swine with Aortic Injury. J Trauma. 2003 May;54(5, Suppl):S110-17.
171. Holcomb JB. Fluid Resuscitation in Modern Combat Casualty Care: Lessons Learned From Somalia. J Trauma. 2003 May;54(5 Suppl):S46-51.
172. Schreiber MA, Holcomb JB, Hedner U, Brundage SI, Macaitis JM, Aoki N, Meng ZH, Tweardy DJ, Hoots K. The Effect of Recombinant Factor VIIa on Noncoagulopathic Pigs With Grade V Liver Injuries. J Am Coll Surg. 2003 May;196(5):691-7.
173. Holcomb JB, McMullin NR, Kozar RA, Lygas MH, Moore FA. Morbidity From Rib Fractures Increases After Age 45. J Am Coll Surg. 2003 Apr;196(4):549-55.
174. Sondeen JL, Pusateri AE, Coppes VG, Gaddy CC, Holcomb JB. Comparison of 10 different Hemostatic Dressings in an Aortic Injury. J Trauma. 2003 Feb;54(2):280-5.
175. Balogh Z, McKinley BA, Cocanour CS, Kozar RA, Holcomb JB, Ware DN, Moore FA. Secondary Abdominal Compartment Syndrome is an Elusive Early Complication of Traumatic Shock Resuscitation. Am J Surg. 2002 Dec;184(6):538-43;discussion 543-4.
176. McHenry TP, Holcomb JB, Aoki N, Lindsey RW. Fractures With Major Vascular Injuries from Gunshot Wounds: Implications of surgical sequence. J Trauma. 2002 Oct;53(4):717-21.
177. Schreiber MA, Holcomb JB, Hedner U, Brundage SI, Macaitis JM, Hoots K. The effect of recombinant factor VIIa on coagulopathic pigs with grade V liver injuries. J Trauma. 2002 Aug;53(2):252-7; discussion 257-9.
178. Carrico CJ, Holcomb JB, Chaudry IH; PULSE Trauma Work Group. Post Resuscitative and Initial Utility of Life Saving Efforts. Scientific Priorities and Strategic Planning for Resuscitation Research and Life Saving Therapy Following Traumatic Injury: Report of the PULSE Trauma Work Group. Acad Emerg Med. 2002 Jun;9(6):621-6.
179. Kheirabadi B, Pearson R, Tuthill D, Rudnicka K, Drohan W, Holcomb JB, MacPhee MJ. Comparative Study of the Hemostatic efficacy of a new human fibrin sealants: Is an antifibrinolytic agent necessary? J Trauma. 2002 Jun;52(6):1107-15.
180. Holcomb JB, Dumire RD, Crommett JW, Stamateris CE, Fagert MA, Cleveland JA, Dorlac GR, Dorlac WC, Mattox KL. Evaluation of Trauma Team. Performance Using An Advanced Human Patient Simulator For Resuscitation Training. J Trauma. 2002 Jun;52(6):1078-1085; discussion 1085-6.
181. Schreiber MA, Holcomb JB, Conaway CW, Campbell KD, Wall M, Mattox KL. Military trauma training performed in a civilian trauma center. J Surg Res. 2002 May; 104(1):8-14.
182. Carrico CJ, Holcomb JB, Chaudry IH. PULSE Trauma Work Group. Scientific priorities and strategic planning for resuscitation research and life saving therapy following traumatic injury: Report of pulse trauma work group. Post Resuscitative and Initial Utility of Life Saving Efforts. Shock. 2002 Mar;17(3):165-8.
183. Crommett JW, McCabe D, Holcomb JB. Training for the transport of mechanically ventilated patients. Respir Care Clin N Am. 2002 Mar;8(1):105-18.
184. Roberts DA, Holcomb JB, Parker BE, Sondeen JL, Pusateri AE, Brady WJ, Young JS. The use of polynomial neural networks for mortality prediction in uncontrolled venous and arterial hemorrhage. J Trauma. 2002 Jan;52:130-5.
185. McHenry T, Simmons S, Alitz C, Holcomb JB. Forward surgical stabilization of penetrating lower extremity fractures: Circular casting versus external fixation. Mil Med. 2001 Sept:166(9):791-95.
186. Kheirabadi BS, Tuthill D, Bayer V, Pearson R, Hill CR, Beall D, Drohan B, MacPhee MJ, Holcomb JB. Metabolic and hemodynamic effects of CO2 pneumoperitoneum in a controlled hemorrhage model. J Trauma. 2001 Jun;50(6):1031-43.
187. Holcomb JB, Hirshberg A, Helling TS. Military, Civilian, and Rural Application of the Damage Control Philosophy. Mil Med. 2001 Jun;166(6):490-493.
188. Hirshberg A, Holcomb JB, Mattox KL. Hospital Trauma Care in Multiple Casualty Incidents: A Critical view. Ann Emerg Med. 2001 Jun;37(6):647-52.
189. Martinowitz U, Holcomb JB, Pusateri AE, Stein M, Onaca N, Freidman M, Macaitis JM, Castel D, Hedner U, Hess JR. Intravenous rFVIIa Administered for Hemorrhage Control in Hypothermic Coagulopathic Swine with Grade V Liver Injuries. J Trauma. 2001 Apr:50(4);721-729.
190. Wall MJ, Hirshberg A, LeMaire SA, Holcomb JB, Mattox KL. Thoracic aortic and thoracic vascular injuries. Surg Clin N Amer. 2001;81(6);1375-94.
191. Pusateri AE, Holcomb JB, Harris RA, MacPhee MJ, Charles NC, Beall LD, Hess JR. Effect of Fibrin Bandage Fibrinogen Concentration on blood Loss after grade V liver injury in swine. Mil Med. 2001 Mar:166(3):217-222.
192. Pusateri AE, Holcomb JB, Bhattacharyya SN, Harris RA, Gomez RR, MJ MacPhee, JI Enriquez, AV Delgado, NC Charles, JR Hess. Different Hypotensive Responses To Intravenous Bovine And Human Thrombin Preparations In Swine. J Trauma. 2001 Jan;50(1):83-90.
193. Aoki N, Wall MJ, Granchi T, Schreiber MA, Holcomb JB, Byrne M, Liscum KR, Goodwin G, Demsar J, Zupan B, Beck JR, Mattox KL. Predictive Model For Survival At The Conclusion Of A Damage Control Laparotomy. Am J Surg. 2000 Dec;180(6):540-45; discussion 544-5.
194. Mabry RL, Holcomb JB, Baker AM, Uhorchak JM, Cloonan CC, Canfield AJ, Perkins DE, Hagmann JH. US Army Rangers in Somalia: An analysis of combat casualties on an urban battlefield. J Trauma. 2000 Sep;49(3):515-28; discussion 528-9.
195. Champion HR, Holcomb JB. Feasibility of Damage Control Surgery in the Management of Military Combat Casualties. Letter to Archives of Surgery in response to Eiseman B, Moore EE, Meldrum DR, Raeburn C. Feasibility of damage control surgery in the management of military combat casualties. Arch Surg. 2000 Aug;136(18):965-7.
196. Cornum RL, Morey AF, Harris R, Gresham V, Daniels R, Knight RW, Beall D, Pusateri A, Holcomb JB, MacPhee M. Does the absorbable fibrin adhesive bandage facilitate partial Nephrectomy? J Urol. 2000;164(3 Pt 1):864-7.
197. Holcomb JB, McClain JM, Beall LD, Pusateri AE, Macaitis JM, Harris RA, MacPhee MJ, Hess JR. Fibrin Sealant Foam Sprayed Directly On Liver Injuries Decreases Blood Loss in Resuscitated Rats. J Trauma. 2000 Aug;49(2):246-50.
198. Dubick MA, Holcomb JB. A review of intraosseous vascular access: Current status and military application. Mil Med. 2000 Jul;165(7):552-59.
199. Butler FK, Hagmann JH, Holcomb JB, et al. Tactical Management of Urban Warfare Casualties in Special Operations. Mil Med. 2000;165 (4, supp:1-48).
200. Martin RR, Alvarez J, Holcomb JB. Civilian urban trauma experience approximates injuries seen in war for abdominal injuries. Current Surgery. 1999;56(7/8):417-419.
201. Holcomb JB, Pusateri AE, Baskin TW, Ellison RW, Macaitis JM, Brinkley WW, Sondeen JL. Hemodynamic and metabolic effects of resuscitation in an uncontrolled hemorrhage model of severe rat liver injury. Current Surgery. 1999;56(7/8):423-427.
202. Nessen SC, Holcomb JB, Tonkinson B, Hetz SP, Schreiber MA. Early laparoscopic Nissen fundoplication for recurrent reflux esophagitis: A cost-effective alternative to omeprazole. JS Laparoendoscopic Surgeons. 1999;3(2):103-106.
203. Holcomb JB, Pusateri AE, Harris RA, Reid TJ, Beall LD, Hess JR, MacPhee MJ. Dry fibrin sealant dressings reduce blood loss, resuscitation volume and improve survival in hypothermic coagulopathic swine with grade V liver injuries. J Trauma. 1999 Aug;47(2):233-40; discussion 240-2.
204. Lein B, Holcomb JB, Brill S, Hetz SP, McCrorey T. Removal of unexploded ordnance from patients: a 50 year military experience and current recommendations. Mil Med. 1999;164(3):163-65.
205. Holcomb JB, Pusateri AE, Harris RA, Charles NC, Gomez RR, Cole JP, Beall Ld, Bayer V, MacPhee MJ, Hess JR. Effect of Dry Fibrin Sealant Dressings Versus Gauze Packing on Blood loss in Grade V Liver Injuries in Resuscitated Swine. J Trauma. 1999 Jan;46(1);46-57.
206. Tock B, Drohan W, Hess J, Pusateri A, Holcomb JB, MacPhee M. Hemophilia and advanced fibrin sealant technologies. Hemophilia. 1998;4:449-455.
207. Holcomb JB, MacPhee M, Hetz S, et al. Efficacy of a Dry Fibrin Sealant Dressing for Hemorrhage Control after a Ballistic Injury. Arch Surg. 1998;133(1):32-35.
208. Holcomb JB, Pusateri A, MacPhee M, Hess J. New Technologies in Hemorrhage Control. Curr Opin Crit Care. 1997;3:488-93.
209. Holcomb JB, Pusateri AE, Hetz SP, Harris RA, Hess JR, MacPhee MJ, Tock BB, Drohan WN. Implications of New Fibrin Sealant Technology for Trauma Surgery. Surg Clin North Am. 1997 Aug;77(4):943-52.
210. Hetz SP, Holcomb JB. Combined Laparoscopic Exploration and Repair of Inguinal Hernias. J Am Coll Surg. 1996 Apr:364-366.
211. Geer D, Arnaud G, Beitler A, Holcomb JB, et al. Colonic Volvulus. The Army Medical Center Experience 1983-1987. Am J Surg. 1991 May;57(5):295-300.
Chapters/Books
1. Jenkins DH, Holcomb JB. Resuscitation. Chapter 162 in Irwin RS, Rippe JM, eds. Intensive Care Medicine, 6th Edition. Philadelphia, Pa, Lippincott Williams & Wilkins, 2008.
2. Zimrin AB, Holcomb JB, Hess Jr. Hemorrhage Control and Thrombosis Following Severe Injury. Chapter 47 in Kitchens CS, Alving BM, Kestler CM eds. Consultative Hemostasis and Thrombosis, 2nd Edition. Philadelphia, Saunders, 2006.
3. McMullin NR, Holcomb JB, Sondeen J. Hemostatic Resuscitation. In: Yearbook of Intensive Care and Emergency Medicine 2006. Springer-Verlag Berlin Heidelberg, 2006;265-278.
4. Holcomb JB. In Valadka A, ed. Neurosurgery, Clinical Practice. Simultaneous Intracranial and Abdominal Injuries: Which Gets Operated on First, and Which Has the Higher Treatment Priority? In Valadka AB and Andrews BT (eds). Neurotrauma: Evidence Based Answers to Common Questions. Chapter 31, pp 175-178., New York:Thieme 2005.
5. Baskin TW, Holcomb JB. Bombs, Mines, Blast, Fragmentation and Thermobaric mechanisms of injury. In Mahoney PF, Ryan JM, Brooks AJ, Schwab CW (eds.),Ballistic Trauma: A Practical Guide. 2nd ed., Springer-Verlag, 2005.
6. Mabry R and Holcomb JB. Trauma Assessment. In Whitlock WL, ed. Special Operations Forces Medical Handbook (Chapter #), pp. Jackson, WY: Teton New Media, 2001.
7. Greydanus D and Holcomb JB. Field Appendectomy. In Whitlock WL, ed. Special Operations Forces Medical Handbook (Chapter #), pp. Jackson, WY: Teton NewMedia, 2001.
Location & Contact
6431 Fannin Street
MSB 4.020
Houston, Texas 77030
Tel: 713-500-7200
Fax: 713-500-7213
Contact Information
- John B. Holcomb, MD, FACS
Director, Center for Translational Injury Research
Professor and Vice Chair of the Department of Surgery,
Chief of the Division of Acute Care Surgery- Department of Surgery
The University of Texas Medical School at Houston
6431 Fannin Street, MSB 4.170
Houston, Texas 77030phone: (713) 500-7218
fax: (713) 500-7213
e-mail: John.Holcomb@uth.tmc.edu
Administrative Coordinator:
Monique Nunley
