The Department of Pediatric Surgery at the University of Texas Medical School at Houston
Department of Pediatrics
The Department of Pediatric Surgery

Training Program

 


Research Opportunities

Basic Science Research

Dr. Charles S. Cox, Jr.Dr. Charles S. Cox, Jr. directs the Translational Laboratory at the UT-Houston Medical School with a focus on traumatic injury and intestinal motility. Additionally, Dr. Cox’s group is studying how stem cells can be used to heal brain injury as well as how fluid resuscitation effects gut motility. This work has been described in a number of publications that are listed with their links below.

Ewing-Cobbs L, Prasad M, Kramer L, Cox CS, Baumgartner JE, Fletcher S, Mendez D, Zhang X, Swank P. Late intellectual outcomes following inflicted and non-inflicted traumatic brain injury sustained during early childhood. Pediatrics.Oct;105(4 Suppl):287-96, 2006.

Radhakrishnan RS, Xue H, Moore-Olufemi SD, Weisbrodt NW, Moore FA, Allen SJ, Laine GA, Cox CS Jr. Hypertonic saline resuscitation prevents hydrostatically-induced intestinal edema and ileus. Crit Care Med 34:1713-1718, 2006.

Moore-Olufemi SD, Xue H, Attuwaybi BO, Fischer UM, Harari Y, Oliver DH, Weisbrodt NW, Allen SJ, Moore FA, Stewart RH, Laine GA, Cox CS. Resuscitation-induced gut edema and intestinal dysfunction. J Trauma 58:264-270, 2005.

Dr. Andrea Hayes-JordanDr. Andrea Hayes-Jordan directs the Pediatric Basic Science Surgical Laboratory at the MD Anderson Cancer Center with a focus on pediatric soft tissue sarcomas. Additionally, Dr. Hayes-Jordan’s group is studying the role and origin of pericytes in pulmonary metastasis in Ewing’s Sarcoma attempting to identify angiogenic regulators of pulmonary metastasis. This work has been described in a number of publications that are listed with their links below.

Harting MT, Blakely ML, Jaffe N, Cox CS, Hayes-Jordan A, Benjamin RS, Raymond AK, Andrassy RJ, Lally KP. Long term survival after aggressive resection of pulmonary metastasis among children and adolescents with osteosarcoma. J Pediatr Surg Jan 41(1):194-9, 2006.

Hayes-Jordan A, Doherty DK, West SD, Raney RB, Blakely ML, Cox CS, Andrassy RJ, Lally KP. Outcome after surgical resection of recurrent rhabdomyosarcoma. J Pediatr Surg Apr 41(4):633-638, 2006.

Clinical Research

Dr. Kevin P. LallyDr. Kevin P. Lally directs the Pediatric Surgery Clinical Research Program at the UT Medical School at Houston with a focus on congenital abnormalities and neonatal surgical issues. Dr. Lally is a world expert in the management and outcomes of infants affected with congenital diaphragmatic hernias. Additionally, Dr. Lally focuses on necrotizing enterocolitis and ECMO. This work has been described in a number of publications that are listed with their links below.

Lally KP, Lally PA, Van Meurs KP, Bohn DJ, Davis CF, Rodgers B, Bhatia J, Dudell G; Congenital Diaphragmatic Hernia Study Group. Treatment evolution in high-risk congenital diaphragmatic hernia: ten years' experience with diaphragmatic agenesis.
Ann Surg. 2006 Oct;244(4):505-13.

Blakely ML, Tyson JE, Lally KP, McDonald S, Stoll BJ, Stevenson DK, Poole WK, Jobe AH, Wright LL, Higgins RD; NICHD Neonatal Research Network. Laparotomy versus peritoneal drainage for necrotizing enterocolitis or isolated intestinal perforation in extremely low birth weight infants: outcomes through 18 months adjusted age. Pediatrics Apr;117(4):e680-7, 2006.

Khan AM, Lally KP. The role of extracorporeal membrane oxygenation in the management of infants with congenital diaphragmatic hernia. Semin Perinatol 2005 Apr;29(2):118-22. (Review)

Dr. Richard AndrassyDr. Richard Andrassy's research focuses on pediatric surgical oncology and nutrition with a special focus on sarcoma. This work has been described in a number of publications that are listed with their links below.

Rodeberg D, Arndt C, Breneman J, Lyden E, Donaldson S, Paidas C, Andrassy R, Meyer W, Wiener E. Characteristics and outcomes of rhabdomyosarcoma patients with isolated lung metastases from IRS-IV. J Pediatr Surg 2005 Jan;40(1):256-62.

Harting MT, Blakely ML, Herzog CE, Lally KP, Ajani JA, Andrassy RJ. Treatment issues in pediatric gastric adenocarcinoma. J Pediatr Surg 2004 Aug;39(8):e8-10.

Andrassy RJ, Wiener ES, Raney RB, Lawrence W, Lobe TE, Corpron CA, Maurer HM. Thoracic sarcomas in children. Ann Surg 1998 Feb;227(2):170-3.

Andrassy RJ, Chwals WJ. Nutritional support of the pediatric oncology patient.
Nutrition 1998 Jan;14(1):124-9. (Review)

Dr. KuoJen TsaoDr. KuoJen Tsao’s research focuses on clinical and translational approaches to pediatric surgery with a emphasis on prospective clinical trials. His clinical interests include advanced minimally invasive surgery and fetal intervention. This work has been described in a number of publications that are listed with their links below.

Tsao K, Hirose S, Sandberg PL, Filly RA, Albanese CT, Harrison MR, Farmer DL. Selective Reduction of Acardiac Twin by Radiofrequency Ablation. American Journal of Obstetrics and Gynecology, 187(3Pt1):635-40, 2002.

Tsao K, Hawgood S, Dhawan K, Hirose S, Sydorak R, Albanese CT, Farmer DL, Harrison MR, Lee H. Resolution of Hydrops Fetalis in Congenital Cystic Adenomatoid Malformation after Prenatal Steroid Therapy. Journal of Pediatric Surgery, Mar 38(3), 508-10, 2003.

Tsao K, Lee H. Extrapleural Thoracoscopic Repair of Esophageal Atresia with Tracheo-Esophageal Fistula. Pediatric Surgery International, Apr 21(4):308-10, 2005.

Tsao K, St. Peter SD, Sharp SW, Nair A, Ostlie DJ, Holcomb III GW. Current Application of Thoracoscopy in Children. Laparoendoscopic and Advanced Surgical Techniques (in press).

 

Research opportunities are available during the fellowship in both clinical and basic science research. Our faculty have ongoing research studies, and fellows are encouraged to participate in these activities. Preparation of papers and participation in presentations are encouraged as well.